电感耦合等离子体发射光谱法同时测定奥贝胆酸中硼和钯的-中国测试.pdfVIP

第43卷第2期 中国测试 Vol.43 No.2 2017年2月 CHINA MEASUREMENT TEST February，2017 doi院10.11857/j.issn.1674-5124.2017.02.009 电感耦合等离子体发射光谱法同时测定 奥贝胆酸中硼和钯的含量 陈晓霞袁 杨晓华 （河北科技大学 河北省分析测试研究中心，河北 石家庄 050018） 摘 要院建立电感耦合等离子体发射光谱法同时测定奥贝胆酸中硼和钯含量的方法遥 奥贝胆酸样品经过微波消解处 理后袁采用电感耦合等离子体发射光谱法测定遥通过实验确定硼的分析谱线为249.77nm袁钯的分析谱线为340.46nm遥方 法学验证的结果表明袁测定奥贝胆酸中硼和钯的检出限分别为0.02mg/kg和0.09mg/kg袁线性良好袁相关系数分别为 0.9999和0.9998袁RSD分别为0.68%和0.52%袁加标回收率分别为 100.7%耀110.6%和96.7%耀110.6%遥 该方法简化样 品的前处理过程袁具有快速尧准确尧灵敏度高及两种元素可同时测定的优点袁可用于奥贝胆酸样品中残留硼和钯的测 定遥 关键词院电感耦合等离子体发射光谱曰奥贝胆酸曰硼曰钯 文献标志码院A 文章编号院1674-5124渊2017冤02-0047-03 Determination of B and Pd in obeticholic acid by ICP-AES CHEN Xiaoxia，YANG Xiaohua （Hebei Research Center of Analytical Testing，Hebei University of Science Technology， Shijiazhuang 050018，China） Abstract: This work proposed an ICP-AES method for simultaneous determination of trace amounts of B and Pd in obeticholic acid. The obeticholic acid was treated by microwave digestion，the B and Pd were analyzed by inductively coupled plasma atomic emission spectrometry. The analysis spectral lines of B and Pb were respectively determined by experiments，249.77nm for B and 340.46 nm for Pb. The limit of detection was 0.02mg/kg and 0.09mg/kg. The method had a good linear correlation，with the correlation coefficient being 0.9999 and 0.9998 for B and Pd determination in obeticholic acid. The relative standard deviation was 0.68% and 0.52%，and recovery rate was 100.7%-110.6% and 96.7%-110.6%. This method was proved to be