epinephrine肾上腺素含量英文.pdfVIP

View Article Online / Journal Homepage / Table of Contents for this issue Analyst, July 1998, Vol. 123 (1461–1463) 1461 Quantitative assay for epinephrine in dental anesthetic solutions by capillary electrophoresis a a †b *a Philip Britz-Mckibbin , Andrea R. Kranack , Alison Paprica and David D. Y. Chen a Department of Chemistry, University of British Columbia, Vancouver, BC, V6T 1Z1, Canada. E-mail: chen@chem.ubc.ca b Astra Pharma Inc., 1004 Middlegate Road, Mississauga, Ontario, L4Y 1Z1, Canada A simple and robust method for the separation and USA) and 1 mm ethylenediaminetetraacetic acid (EDTA) (BDH quantification of epinephrine in dental anesthetic Chemicals, Toronto, Ontario, Canada). The pH of the back- solutions was developed. The method allows the direct ground electrolyte was adjusted to 10.1 by using 0.1 m NaOH injection of high salt solutions without sample (BDH Chemicals). Standard epinephrine [epinephrine ()-hy- . 4 pre-treatment. Large sample plugs (5.7% of the total drogentartrate, Sigma Chemical) solutions were made by 2 : 5 capillary length) are used for epinephrine determination appropriate dilution of a stock standard solution of 50 g ml1 3 : 3 by selective analyte focusing in capillary electrophoresis. epinephrine free base