时间分辨荧光免疫法与电化学发光法检测结直肠-世界华人消化杂志.pdfVIP

ISSN 1009-3079 CN 14-1260/R 世界华人消化杂志 2005年12月15日 第13卷 第23期 2799 • 研究快报 BRIEF REPORT • 时间分辨荧光免疫法与电化学发光法检测结直肠肿瘤标志 CEA 的比较 张青云, 孙 丽, 张书耕, 王 琼 张青云, 北京大学临床肿瘤学院 北京肿瘤医院检验科 北京市肿瘤防治 thy control group (TRFIA: 1.04±0.55 μg/L, ECLIA: 研究所免疫研究室 北京市 100036 孙丽, 锦州医学院生化教研室 辽宁省锦州市 121001 0.71±0.48 μg/L) (P 0.01). The sensitivities of TRFIA 张书耕, 王琼, 北京大学临床肿瘤学院 北京肿瘤医院检验科 北京市 100036 and ELCIA were 60.0% and 66.7%; the specificities 通讯作者: 张青云, 100036, 北京大学临床肿瘤学院, 北京肿瘤医院检验科, 北京市肿瘤防治研究所免疫研究室. qingyzhang@ were 98.3% and 100%; the accuracies were 85.6% 电话: 010 and 88.9%; the positive predictive rates were 94.7% 收稿日期: 2005-09-21 接受日期: 2005-11-12 and 95.2%; and the negative predictive rates were 83.1% and 85.7%, respectively. The results of ELCIA Comparison between time-resolved were better than those of the TRFIA, and they were fluorescence immunoassay and well correlated (r = 0.973 8). There was no significant electro-chemiluminescence difference between the two methods (P 0.05). immunoassay for detection of serum carcinoembryonic antigen in CONCLUSION: There is a good correlation between colorectal carcinoma TRFIA and ECLIA for detection of the serum CEA level. They have high sensitivities and good stabilities, and Qing-Yun Zhang, Li Sun, Shu-Geng Zhang, Qiong Wang