贯穿始终,安全控糖看地特胰岛.pptVIP

另外，研究显示年龄每增长10岁，糖尿病发病风险提高68％1.流行病学调查数据显示随着年龄的增加，老年人患病率高于其他人群。随着社会逐渐老龄化，老年糖尿病患者也不断增加。中国调研数据1显示，20-39岁患者糖尿病发病率为3.2%，40-59岁患者发病率为11.5%，≥60岁的患者发病率上升至20.4%。 * * * 过去的一项大规模多中心研究，纳入6309例儿童1型糖尿病患者调查其血糖控制、低血糖发生率等，结果显示：严重低血糖事件在0~5岁患者中比例（31.2/100患者一年）显著高于年纪稍大的儿童患者（分别为19.7/100患者一年、21.7/100患者一年），p0.05。而严重低血糖常伴随昏迷/抽搐，并影响多个神经系统功能。 Abstract Hypoglycaemia is frequently the limiting factor in achieving optimal glycaemic control. Therefore, insulin therapy, the incidence of hypoglycaemia, and glycaemic control were investigated in 6309 unselected children with type 1 diabetes in a large-scale multicentre study. Using standardised computer-based documentation, the incidence of severe hypoglycaemia, HbA1c levels, insulin regimen, diabetes duration, and the number of patients attending a treatment centre were investigated for the age groups 0-5 years (n =782), 5- 7 years (n =1053), and 7-9 years (n =4474). The average HbA1c level was 7.6% (no significant difference between age groups). Young children had more severe hypoglycaemic events (31.2/100 patient years) as compared to older children (19.7; 21.7/100 patient years, P 0.05) independent of the treatment regimen. Our data suggest that diabetes centres treating less than 50 patients per year have a higher incidence of hypoglycaemia in 0-5-year-old children (43.0/100 patient years) as compared to larger centres (24.1/100 patient years; P 0.0001). Significant predictors of hypoglycaemia were younger age (P 0.0001), longer diabetes duration (P 0.0001), higher insulin dose/kg per day (P 0.0001), injection regimen (P 0.0005), and centre experience (P 0.05). Conclusion: Despite modern treatment, young children have an elevated risk for developing severe hypoglycaemia compared to older children, especially when treated at smaller diabetes centres. The therapeutic goal of carefully regulating metabolic control without developing hypoglycaemia has still not been achieved. Further advances in diabetic treatment may result from giving more att