Forensic Science Presents - Mill Creek High School：法医科学提出了磨溪中学.pptVIP

Collection of DNA Precautions - disposable latex gloves; glasses or goggles; face masks; shoe covers; coveralls; very little personal contact! Packaging – separately in a paper bag or well-ventilated box. Allow swabs to dry 5-10 minutes and place in a manila envelope. Place in refrigerator or cool place. Example A violent murder occurred. The forensics team retrieved a blood sample from the crime scene. They prepared DNA profiles of the blood sample, the victim and a suspect as follows: Was the suspect at the crime scene? Suspects Profile Blood sample from crime scene Victims profile Solving Medical Problems DNA profiles can be used to determine whether a particular person is the parent of a child. A childs paternity (father) and maternity(mother) can be determined. This information can be used in Paternity suits Inheritance cases Immigration cases Example: A Paternity Test By comparing the DNA profile of a mother and her child it is possible to identify DNA fragments in the child which are absent from the mother and must therefore have been inherited from the biological father. Is this man the father of the child? Mother Child Man * * * * * * * * * * Forensic SciencePresents DNA B. History 1. James Watson and Francis Crick—in 1953 discovered the configuration of the DNA molecule. 2. Alec Jeffreys– the first to recognize DNA is unique to everyone. He isolated DNA markers and called them DNA “fingerprints.” A. Terminology Chromosomes –are strands of genetic material (DNA) The avg human chromosome contains 100 million base pairs Genes – fundamental unit of heredity; they instruct cells to make proteins Structure of DNA Nucleotides - the “monomers” of DNA; consist of a 5 carbon sugar, a phosphate group, and a nitrogenous base. ( 4 bases are A,T,G,C ) Double Helix A-T G-C Protein Synthesis . DNA codes for the assembly of Amino acids into proteins, Each sequence of 3 bases codes for a particular Amino Acid (building bloc