COPD临床评估与治疗的热点问题.pptVIP

* Speaker Notes Subjects with bronchitis and nearly normal FEV1 during exacerbations had, on average, 30-fold more eosinophils in their bronchial biopsies than did those examined under baseline conditions (P0.001). Reference Saetta M, Di Stefano A, Maestrelli P, et al. Airway eosinophilia in chronic bronchitis during exacerbations. Am J Respir Crit Care Med 1994;150:1646-1652. With regard to the absolute values of arterial blood gases and spirometric measurements at 10 days, mean forced expiratory flow between 25 and 75% of FVC (FEF25–75%) value in group 3 was significantly higher than th