7-消化系统 2015-6-1.ppt

Chronic pancreatitis Bouts of mild to moderate pancreatic inflammation with continued loss of pancreatic parenchyma and replacement by fibrous tissue Pathogenesis: obscure Clinical features Repeated attacks of various degrees of abdominal pain Mild elevations of serum amylase and lipase levels X-ray reveals calcifications within the pancreas Morphology Fibrosis with chronic inflammatory infiltrate Extensive atrophy of the exocrine glands Carcinoma of the pancreas Carcinoma arising in the exocrine portion of the gland Risk factor: unknown, smoking? Clinical features Pain, jaundice, migratory