葡萄球菌性烫伤样皮肤综合征的回顾与.pdfVIP

332 West China Medical Journal Vol.27 No.3 Mar. 2012 2012 27 3 (SSSS) 1995 12010 1246 SSSS SPSS 13.0 1 6 71.1% SSSS 5 7 d 10 d A Retrospective Analysis of Patients with Staphylococcal Scalded Skin SyndromeAI Qian, LÜ Jun, LEI Shu-ying, CHEN Shang-zhou. Department of Dermatology, Enshi Central Hospital, Enshi, Hubei 445000, P. R. China Abstract Objective To discuss and analyze the inducing factors, clinical manifestations, diagnosis characteristics and optimal treatment of staphylococcal scalded skin syndrome (SSSS), so as to improve future clinical work. Methods The data of 46 child patients with clinically diagnosed SSSS from January 1995 to December 2010 were analyzed retrospectively with the application of SPSS 13.0 for windows software. ResultsThe majority (71.14%) of the patients was consisted of otherwise healthy children ranging from 1 to 6 years of age. Infection was identifi ed as the main inducing factor, and early manifestations including peri-orbital and perioral erythema with radiating crack were found to be of important diagnostic value. Early treatment with potent antibiotics and c-type globulin was noted to have significant therapeutic effects. ConclusionsSSSS is a rare skin disease, and the current diagnosis is mainly based on its typical clinical manifestation and positive bacteria culture from the infection lesions. Early initiation of potent sensitive antibiotics along with c-type globulin can effectively relieve symptoms and shorten the duration of symptoms. Generally, the disease begins to recover after treatment for 5 to 7 days, heals within 10 days, and the long-term complications