动态监测感染性休克患儿血小板计数及平均体积的临床意义.pdfVIP

第 29 卷第 4 期 广 东 医 学 院 学 报 Vol. 29 No. 4 370 2011 年 8 月 JOURNAL OF GUANGDONG MEDICAL COLLEGE Aug. 2011 动态监测感染性休克患儿血小板计数及平均体积的临床意义 邓顺周，林建 国，游锦安，李　勤，张春 兰 （南方医科大学附属新会 医院儿科，广东江 门 529 100） 摘　 要： 目的 探讨动态监测感染性休克患儿血小板(PLT)计数及平均血小板体积(MPV)的临床意义 。方法 检测 53例感染性休克患儿(代偿期38例，失代偿期 15例)入 院后 1、24 、72、120 h 的PLT计数 、MPV，并与 同期50例健康儿作 对照 。结果 感染性休克患儿入 院时PLT计数低于对照组，而MPV高于对照组(P0.01)，其 中失代偿期组更 明显 。死亡 组PLT计数在各时点均低于存活组，但MPV均高于存活组(P0.01) 。结论 感染性休克患儿PLT计数、MPV 的动态变化有 助于判断病情严重程度及预后。 关键词：感染性休克；血小板计数；平均血小板体积；儿童 + 中图分类号：R631 .4 文献标识码：A 文章编号：1005-4057(2011)04-370-03 DOI: 10.3969/j.issn.1005-4057.2011.04.005 Dynamic monitoring of platelet count and mean platelet volume in children with septic shock DENG Shun-zhou, LIN Jian-guo, YOU Jin-an, LI Qin, ZHANG Chun-lan (Department of Pediatrics, Affiliated Xinhui Hospital of Southern Medical University, Jiangmen 529 100, China) Abstract: Objective To observe the clinical significance of dynamic monitoring of platelet (PLT) count and mean platelet volume (MPV) in children with septic shock. Methods PLT count and MPV were detected in 53 children (compensated shock, 38; decompensated shock, 15) with septic shock at 1, 24, 72, 120 h after admission. The controls included 50 healthy children at the same time. Results Compared with control group, PLT count decreased, but MPV increased in shock group on admission (P0.01), especially in those with decompensated shock. PLT count in dead group was significantly lower than that in survival group at all time-points, but MPV wsa just the opposite (P0.01). Conclusion Dynamic change of PLT count and MPV may be helpful for judging the severity and prognosis in children with septic shock. Key words: septic shock; platelet count; mean platelet volume;