696例手足口病临床回顾性分析.docVIP

精品论文 参考文献 696例手足口病临床回顾性分析 邹永胜 牟花妮 蒋玉凤（通讯作者） 　　（泸州医学院附属医院感染病科 四川泸州 646000） 　　【摘要】目的 总结手足口病的临床特点，加深对重症手足口病的认识和早期识别，提高诊疗水平。方法 对2009年1月至2013年12月收治的696例手足口病患者的临床资料进行回顾性分析。结果 手足口病的高发年龄为3岁以下，流行高峰期为每年5-7月，本组696例手足口病患者中，一般病例680例(占97．7％)，均全部治愈，重症病例16例(占2.3％)，病死4例（占25.0%）。结论 通过对696例手足口病患者临床资料进行回顾性分析，提高了对重症手足口病的认识，为早期识别重症手足口病及降低重症手足口病病死率积累了经验。 　　【关键词】手足口病 临床特点 回顾性分析 　　【中图分类号】R587.2 【文献标识码】A 【文章编号】2095-1752（2014）09-0021-02 　　 　　Retrospective analysis of 696 cases of hand-foot-and-mouth disease 　　ZOU Yongsheng, Mou Huani, JIANG Yufeng 　　Department of Infectious Disease, Affiliated Hospital of Luzhou Medical College, Sichuan Province ,Luzhou 646000,China 　　【Abstract】 Objective To concluse the clinical features of hand-foot-and-mouth disease（HFMD）, thus to deepen understanding and early discrimination of severe hand-foot-and-mouth disease ,and to improve its diagnosis and treatment .Methods: The clinical data of 696 cases of HFMD were treated from January 2009 to December 2013,all were retrospectively analyzed. Results: The high-risk age of HFMD was aged below 3 years old, and the peak of the epidemic was in the period between May and July. Among this group of 696 cases ,680(accounting for 97.7%)were general cases and 16(2.3％) were severe cases. All the general patients were all cured.4 severe patients died. Conclusion :Retrospective analysis of 696 cases of HFMD improves our understanding of severe hand-foot-and-mouth disease and accumulate experience for early discrimination of severe hand-foot-and-mouth disease and reduce death rate of severe cases of HFMD. 　　【Key words】 Hand-foot-and-mouth disease Clinical features Retrospective analysis 　　手足口病(Hand，foot，and mouth disease, HFMD)是全球性传染病，世界大部分地区均有此病流行的报导。1957年新西兰首次报导，1958年分离出柯萨奇病毒，1959年提出HFMD命名。EV71感染与Cox A16感染交替出现，成为手足口病的主要病原体[1]。我国自1981年在上海始见本病，2008年3月至5月3日安徽省阜阳由EV71病毒造成手足口病暴发流行，22例重症患者死亡，一时间引起社会恐慌，各级卫生部门高度重视把手足口病列为丙类传染病，按乙类上报[2]，同时我院的所有手足口病患者均收入感染病科统一隔离诊治。为提高