- 1、本文档共6页,可阅读全部内容。
- 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多
心血管英语译文
The significance of plasma interleukin-8 variety in patients with coronary heart disease pre- and pro-coronary intervention??? ABSTRACT?? Coronary heart disease (CHD) has been the first critical disease of human being around the world. Percutaneous coronary intervention (PCI) has established an effective procedure for CHD. However, there were still some problems contributed to intervention related sever complications such as acute occlusion and restenosis pre- and pro-procedure.?? Since Ross initiatively suggested that atherosclerosis be a chronic inflammatory disease of the vessel wall in 1973, there have been progressive reports about the relations between inflammatory activation and coronary atherosclerosis. Recent data indicate that percutaneous transluminal coronary angioplasty (PTCA) can elicit an activation of inflammatory responses; preprocedural plasma C-reactive protein (CRP) level appear to be an independent predictor of complications and late restenosis in patients with PCI. However, CRP as a marker of inflammatory response cannot reflect the initial mechanism of inflammation and the relation between the inflammatory cells and the cytokines. Furthermore, the predictive value for clinical outcome or the guidance for prevention of complications was no precise. Lately study revealed that Interleukin-8 (IL-8), a powerful regulator of immunology and inflammation, is a mediator for the inflammation evoked by the tumor necrotic factor (TNF)、 interleukin-1 and interleukin-6. The major bioactivity of IL-8 is as an attractant activating neutrophiles to secrete adherent factors, further eliciting the up-graduation of β〓-integrin Mac-1 (CD11b/CD18) on neutrophiles. IL-8 is believed a key factor during the cascade of coagulation factors and cytokines. Therefore, The consistent studies on the regulations of IL-8 and other cytokines in patients with coronary heart disease pre- and pro-PCI were performed. The relationships between IL-8 and the early complicati
文档评论(0)