参松养心胶囊对特发性室性早搏不同早搏负荷患者窦性心率震荡影响.docVIP

精品论文 参考文献 参松养心胶囊对特发性室性早搏不同早搏负荷患者窦性心率震荡影响 吴陈棠（通讯作者） 叶巍 陈雪云 　　（福建医科大学附属闽东医院心内科 福建宁德 355000） 　　【摘要】目的：评价参松养心胶囊对特发性室性早搏（IPVCs）不同早搏负荷患者窦性心率震荡（HRT）的影响。方法：按不同早搏负荷，将94例IPVCs患者分为高负荷组30例、中负荷组36例、低负荷组28例，比较各组参松养心胶囊治疗前后HRT参数震荡初始（TO）和震荡斜率（TS）变化。结果：三组治疗后，低负荷组TO、TS无明显改善（P＞0.05），高、中负荷组TO、TS均有明显改善（P均lt; 0.05），尤以高负荷组改善更显著。结论：参松养心胶囊能改善IPVCs高、中早搏负荷患者的HRT，早搏负荷越重其改善程度越佳；HRT改善程度可作为药物治疗IPVCs的疗效衡量指标。 　　【关键词】参松养心胶囊 窦性心率震荡 室性早搏???特发性 　　【中图分类号】R96 【文献标识码】A 【文章编号】2095-1752（2014）03-0090-02 　　Effect of Shengsongyangxin capsule therapy on heart rate turbulence of patients 　　with idiopathic premature ventricular contractions 　　Wu Chen-tang，Ye Wei，Chen Xue-yun 　　(Department of Cadiology, The Mindong Affiliated Hospital of Fujian Medical University, Ningde, Fujian 355000, China) 　　Corresponding author: Wu Chen-tang,Email:wuchentang2012@163.com 　　【Abstract】Objective: To explore the effect of heart rate turbulence (HRT) in patients with different degree load of idiopathic premature ventricular contractions (IPVCs) after Shengsongyangxin capsule therapy. Methods: A total of 94 patients with IPVCs was divided into three groups by the load of contractions in different degrees: high-load group(n=30), moderate-load group(n=36)and low-load group(n=28), compared the change in values of turbulence onset (TO) and turbulence slope (TS) of HRT parameters amongst different groups before and after Shengsongyangxin capsule treatment. Results: There were significantly improved of TO and TS of the moderate-load and high-load groups, compared to pre therapy (P﹤0.05), especially high-load group; While, there were no significantly improved of TO and TS of the low-load group, compared to pre therapy (P﹥0.05). Conclusions: Shengsongyangxin capsule therapy could improve the HRT of patients with moderate-load or high-load IPVCs，the larger the load, the more the improvement; The scale of improvement of HRT could be a good maker to assess the effectiveness of drug