3.0 T MRI动态增强扫描对乳腺微钙化病变的鉴别诊断价值.docVIP

3.0 T MRI动态增强扫描对乳腺微钙化病变的鉴别诊断价值 郑春红 张玉琴 方舞红 李华灿 福建中医药大学附属第二人民医院影像科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的 :探讨3.0 T MRI动态增强扫描对乳腺微钙化病变的诊断价值。方法 :回顾性分析经病理证实的乳腺X线影像报告和数据系统 (BI-RADS) 35级微钙化病变70例, 均行乳腺3.0 T MRI动态增强扫描。以病理结果作为金标准, 计算2种方法的诊断敏感度和特异度, 并进行比较。结果:70例中恶性病灶22例, 良性48例。MRI对70例微钙化病灶强化特征进行分级:1级10例, 均为良性;2级26例, 均为良性;3级10例, 良性9例, 恶性1例;4级12例, 良性3例, 恶性9例;5级12例, 均为恶性。MRI动态增强扫描与X线摄影对微钙化诊断敏感度差异无统计学意义 (P0.05) , 特异度差异有统计学意义 (P0.01) 。结论:MRI动态增强扫描对乳腺微钙化患者的临床进一步处理具有一定的指导意义。 关键词： 乳房X线摄影术; 微钙化; 磁共振成像; 作者简介：郑春红, E-mail:925970882@。 收稿日期：2017-05-05 Diagnostic value of 3.0 T DCE-MRI in patients with microcalcifications on mammography ZHENG Chunhong ZHANG Yuqin FANG Wuhong LI Huacan Department of Radiology, the Second Peoples Hospital Affiliated of Fujian University of Traditional Chinese Medicine; Abstract： Objective:To investigate the diagnostic value of 3.0 T DCE MRI in patients presenting with microcalcifications on mammography. Methods :70 cases with microcalcifications (BI-RADS category 35) who underwent mammography and 3.0 T DCE-MRI were retrospcetively analyzed. With histopathological diagnosis as golden standerd, the sensitivity and specificity of the two image methods were calculated and compared with χ2 test. Results:Pathologic examination showed 48 benign lesions and 22 malignant lesions in 70 patients. The difference for specificity between the two methods was statistical significant, but not for sensitivity. Conclusions:DCE-MRI can give recommendations for clinical further treatment to patients with microcalcifications. Keyword： Mammography; Microcalcifications; Magnetic resonance imaging; Received： 2017-05-05 微钙化是乳腺癌的常见X线征象, 主要见于早期乳腺癌, 尤其是导管内癌约70%表现为微钙化。乳腺X线摄影对微钙化诊断的特异度为10%~60%[1]。MRI动态增强扫描对乳腺癌, 尤其是浸润性导管癌的临床评估优于乳腺X线和超声, 甚至是乳腺穿刺活检[2], 但对微钙化病变 (尤其是BI-RADS 3~4级微钙化) 的诊断价值仍存在一定争议。现回顾性分析我院2010年1月至2017年3月经乳腺X线摄影检出的70例微钙化患者的MRI表现, 旨在探讨3.0 T MRI动态增强扫描对乳腺微钙化病变良恶性的鉴别诊断价值。 1 资料与方法 1.1 一般资料 70例均为女性, 年龄28~69岁, 平均43岁;乳腺微钙化评分为BI-RADS