3种恶性成分的腮腺区多形性腺瘤癌变1例报告及文献复习.docVIP

3种恶性成分的腮腺区多形性腺瘤癌变1例报告及文献复习 孙兰芳 及昕 史册 韩茹钰 张宁 韩明林 李明贺 韩成敏 吉林大学口腔医院口腔颌面外科 吉林大学口腔医院病理科 吉林大学口腔医院正畸科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的:探讨1例含有3种恶性成分的腮腺区多形性腺瘤癌变 (CXPA) 患者的诊断和预后, 提高临床医生对该病的认识。方法:患者因左腮腺区肿物30年余伴疼痛1个月入院, 经腮腺区彩超检查后行左腮腺区肿物切除术。结果:该患者手术过程顺利, 术后病理诊断为CXPA, 包含非特异性腺癌、导管癌和肌上皮癌3种恶性成分。结论:同时含有多种恶性成分的CXPA临床罕见, 诊断困难, 预后差, 临床医师应提高对该病的认识。 关键词： 多形性腺瘤癌变; 多形性腺瘤; 非特异性腺癌; 导管肿瘤; 肌上皮肿瘤; 作者简介：孙兰芳 (1992-) , 女, 山东省烟台市人, 在读医学硕士, 主要从事口腔颌面外科方面的研究。 作者简介：韩成敏, 教授, 主任医师, 硕士研究生导师 (Tel:0431E-mail:han-cm@) 作者简介：李明贺;主治医师 (Tel:0431 E-mail) 收稿日期：2017-05-06 基金：吉林省科技厅自然科学基金资助课题 (3D515V663431) Carcinoma ex pleomorphic adenoma composed of three malignant components in parotid gland:A case report and literature review SUN Lanfang JI Xin SHI Ce HAN Ruyu ZHANG Ning HAN Minglin LI Minghe HAN Chengmin Department of Oral and Maxillofacial Surgery, Stomatology Hospital, Jilin University; Department of Pathology, Stomatology Hospital, Jilin University; Department of Orthodontics, Stomatology Hospital, Jilin University; Abstract： Objective:To investigate the diagnosis and prognosis of one patient with carcinoma ex pleomorphic adenoma (CXPA) composed of three malignant components in parotid gland, and to raise the clinicians awareness of the disease.Methods:A patient was presented to hospital because of the mass in left parotid gland region for more than 30 years and the accompanied pain lasted for one month.After color ultrasonography, the left parotid gland tumor resection was performed.Results:The operation was successful.The postoperative pathological diagnosis results comfirmed as CXPA, it was composed of three malignant components, including non-specific adenocarcinoma, ductal carcinoma, and myoepithelial carcinoma.Conclusion:CXPA composed of three malignant components at the same time are extremely rare.CXPA is difficult to diagnose and its prognosis is poor.The clinicians are supposed to improve the understanding