物理有机化学PPT-复旦大学-王全瑞 2.Conformational Analysis-2.pptx

ConformationalAnalysis;Baeyer Strain for selected ring sizes;?Baeyer angle strain is calculated from the deviation of the planar bond angles from the ideal tetrahedral bond angle. ? Discrepancies between calculated strain/CH2 and the angle strain results from puckering to minimize van der Waals or eclipsing torsional strain between vicinal hydrogens. ? Why is there an increase in strain for medium sized rings even though they also can access puckered conformations free of angle strain? The answer is transannular strain- van der Waals interactions between hydrogens across the ring.;Cyclopropane: Bonding, Conformation, Carbonium Ion Stabilization;5;6;7;8;9;10;11;13;14;15;16;17;18;20;21;22;23;24;25;26;27;Conformational Analysis: Bicyclic Ring Systems;29;30;31;32;33;34;35;36;37;Predict stereochemistry;39;40;41;42;43;44