头孢噻肟钠治疗儿童细菌性脑膜炎的124例临床分析.docVIP

精品论文 参考文献 头孢噻肟钠治疗儿童细菌性脑膜炎的124例临床分析 龙丽华 梁勇 冉龙国 杨爱梅（贵州省铜仁地区人民医院儿科 贵州铜仁 554300） 【中图分类号】R529 【文献标识码】A【文章编号】1672-5085（2013）1-0164-02 【摘要】 目的 探讨和研究头孢噻肟钠（凯福隆）治疗儿童细菌性脑膜炎的临床疗效。方法 摘取我院近年来收治的124例细菌性脑膜炎患儿作为研究对象，按照随机分组的原则将之分为观察组和对照组各62例，其中观察组在积极常规治疗基础上用头孢噻肟钠进行治疗，对照组则在积极常规治疗基础上采用头孢曲松进行治疗，治疗结束后统计并对比两组患者的治疗结果。结果 两组患儿的治疗总有效率均为100%，但观察组的显效率为93.55%（58/62），对照组的显效率则为70.97%（44/62），观察组明显优于对照组，差异具有统计学意义（P＜0.05）。两组患儿均无明显不良反应发生，在不良反应发生率方面无明显差异，不具有统计学意义（P＞0.05）。结论 头孢噻肟钠治疗儿童细菌性脑膜炎的疗效显著，且安全性较高，值得在临床上加以推广和应用。 【关键词】 头孢噻肟钠 细菌性脑膜炎 儿童病患 Cefotaxime sodium for the treatment of bacterial meningitis in children 124 patients 【Abstract】Objective ：To investigate the clinical efficacy for the treatment of bacterialmeningitis in children and research cefotaxime sodium (claforan). Method ：Admitted to our hospital in recent years clinical data of 124 cases of bacterial meningitis in children as research subjects, divided into observation group and the control group, 62 cases in each in accordance with the principle of randomization observation group actively conventional treatment cefotaxime sodium for treatment, control group actively conventional treatment using ceftriaxone treatment, statistics and compare the treatment outcomes of patients after treatment. Results：Of the treatment of the two groups of children with total efficiency were 100%, but the effective rate is 93.55% of the observation group (58/62), the remarkable efficiency of the control group compared with 70.97% (44/62), the observation group was significantly better than control group, the difference was statistically significant (P lt;0.05). The two groups of children had no significant adverse events, no significant difference in the incidence of adverse reactions was not statistically significant (Pgt; 0.05). Conclusion ：Cefotaxime sodium in the treatment of bacterial meningitis in children a significant effect, and security is high, it is worth to be promoted and applied in the clinical. 儿童细菌性脑膜炎是一种较为严重的感染性疾病，临床上的病死