孕20周前晚期先兆流产应用间苯三酚治疗的效果研究.docVIP

精品论文 参考文献 孕20周前晚期先兆流产应用间苯三酚治疗的效果研究 辰溪县后塘瑶族乡卫生院 湖南辰溪 419500 　　【摘 要】目的 探讨间苯三酚治疗孕20周前晚期先兆流产的临床疗效。方法 选取我院2013年1月-2015年1月收治的孕20周前晚期先兆流产患者135例，将其随机分为观察组（85例）和对照组（50例），观察组孕妇给予间苯三酚治疗，对照组给予静脉滴注硫酸镁，比较两组患者的临床疗效。结果 观察组患者临床症状缓解时间和临床症状完全消失时间均短于对照组（Plt;0.01）；观察组临床有效率95.3%，继续妊娠率91.4%，对照组分别为71.0%和68.0%，组间比较差异显著（Plt;0.01）；观察组治疗期间不良反应发生率为5.9%（5/85），对照组为40%（20/50），两组间比较差异有统计学意义（Plt;0.01）。结论 间苯三酚治疗孕20周前晚期先兆流产患者，药物起效快、临床疗效好、安全性高，具有较高的临床应用价值。 　　【关键词】间苯三酚；先兆流产；临床疗效 　　[Abstract] objective to explore the phloroglucinol treatment the clinical curative effect of late 20 weeks ago threatened abortion. Methods from January 2013 to January 2013 were conceived in the late 20 weeks ago threatened abortion patients 135 cases，will be randomly divided into observation group（85 cases）and control group（50 cases）and observation group of pregnant women to give phloroglucinol treatment，control group given intravenous drip magnesium sulfate，compare the clinical efficacy of two groups of patients. Results the observation group of patients with clinical symptoms and clinical symptoms disappear entirely time are shorter than the control group（P lt; 0.01）；Observation group clinical effective rate was 95.3%，the pregnancy rate was 91.4%，the control group were 71.0% and 68.0% respectively，the more significant difference between groups（P lt; 0.01）；Observation group during treatment the incidence of adverse reactions was 5.9%（5/85），the control group was 40%（20/50），comparing differences between the two groups was statistically significant（P lt; 0.01）. Conclusion phloroglucinol late 20 weeks ago threatened abortion patients treated，drug effect quickly，good clinical curative effect，high security，has high clinical value. 　　[Key words] phloroglucinol；Threatened abortion；Clinical curative effect 　　 　　 　　先兆流产是妇产科常见疾病，孕妇在妊娠12-28周易发生晚期先兆流产，发病率在13%左右[1]。主要临床表现有腰酸、阴道流血、下腹疼痛、阵发性下腹紧缩等。对于仅出现不规则弱宫缩或下腹不适或阴道不规则流血者，可使用宫缩抑制剂进行治疗，均能缓解症状，不过，对于孕20周前晚期先兆流产者，宫缩抑制剂达不到满意效果。国外文献报道，间苯三酚对母婴有较高的安全性，已广泛应用于妇产科、泌尿外科中[2]。本文探讨了间苯三酚治疗孕20周前晚期先兆流产的