中药治疗非小细胞肺癌的临床应用及作用机制研究-天津中草药杂志社.PDFVIP

Drug Evaluation Research 第 39 卷 第 2 期 2016 年 4 月 • 293 • 【综 述 】 中药治疗非小细胞肺癌的临床应用及作用机制研究进展 1 2,3 2,3 2,3* 1* 成娅婷 ，田成旺 ，任 涛 ，张铁军 ，冯 霞 1. 天津大学理学院，天津 300072 2. 天津药物研究院，天津 300193 3. 中药现代制剂与质量控制技术国家地方联合工程实验室，天津 300193 摘 要：非小细胞肺癌是威胁人类健康的重大疾病之一，目前尚缺乏根本的治疗方法。中药因具有整体治疗、有效提高患者 生存质量和生存期等显著特点，在临床上治疗非小细胞肺癌，无论是与手术治疗、化学药物治疗、放射性治疗等联合使用， 还是晚期非小细胞肺癌的维持治疗等方面均得到了广泛的应用。对近年来中药治疗非小细胞肺癌的临床应用及其抗肿瘤作用 机制进行了概述，以期为中药治疗肿瘤的临床应用和中药抗癌新药的研发提供借鉴。 关键词：非小细胞肺癌；中药；肿瘤治疗；临床应用；作用机制 中图分类号：R282.710.5 文献标志码：A 文章编号：1674-6376 (2016) 02-0293-07 DOI: 10.7501/j.issn.1674-6376.2016.02.030 Research progress on clinical application and action mechanism of Chinese materia medica in treatment of non small cell lung cancer 1 2,3 2,3 2,3 1 CHENG Ya-ting , TIAN Cheng-wang , REN Tao , ZHANG Tie-jun , FENG Xia 1. Department of Chemistry, School of Science, Tianjin University, Tianjin 300072, China 2. Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China 3. National Local United Engineering Laboratory of Modern Preparation and Quality Control Technology of Traditional Chinese Medicine , Tianjin 300193, China Abstract: Non-small cell lung cancer (NSCLC) has become one of the major diseases threatening to hum an health. In recently years, there are no fundamental clinical treatment methods for treating it. Owing to many prominent characteristics, such as holistic therapy, improving the life quality and overall survival of the patients, Chinese materia medica (CMM) have been widely applied in clinic treatment of NSCLC. This article outlined the clinical application and antitumor mechanism of CMM in treatment of NSCLC, which was looking forward to provide reference for the res