富马酸比索洛尔治疗老年高血压伴心功能不全患者的临床疗效.docVIP

精品论文 参考文献 富马酸比索洛尔治疗老年高血压伴心功能不全患者的临床疗效 南京市六合区人民医院 心血管内科 211500 【摘 要】目的：研讨老年高血压病伴心功能不全患者运用富马酸比索洛尔片治疗的临床价值。方法：从我院2013年3月-2016年3月选取68例老年高血压病伴心功能不全患者做随机非盲法分组试验，Ⅰ组34例接受常规对症治疗，Ⅱ组34例在上述基础治疗下接受富马酸比索洛尔片用药，对该两种方案的临床应用情况作评估。结果：两组接受治疗后的血压水平基本无差异，对比统计学不成立（P＞0.05）。治疗前，两组的LVEDV、LVESV、LVEF及E/A指标相比差异不大，统计学不成立（P＞0.05），治疗后，Ⅱ组上述指标与Ⅰ组相比均显著改善，统计学成立（P＜0.05）。结论：对老年高血压病伴心功能不全患者运用富马酸比索洛尔片治疗，可有效改善患者心功能，并保持其血压的平稳，值得推荐。 【关键词】高血压病；心功能不全；富马酸比索洛尔片；临床价值 Clinical effect of bisoprolol fumarate in treating elderly patients with hypertension and cardiac insufficiency 【Abstract】Objective: To discuss the clinical effect of bisoprolol fumarate in treating elderly patients with hypertension and cardiac insufficiency. Methods: From March in 2013 to March in 2016, 68 elderly patients with hypertension and cardiac insufficiency were divided into Ⅰ, Ⅱ group (with 34 cases in each group) with randomized not blind trials. Ⅰ group received routine treatment, and Ⅱ group received bisoprolol fumarate upon routine treatment, then the implementation effect of patients in this two options were evaluated. Results: After treatment, the blood pressure of the two groups was statistically insignificant (P gt; 0.05). Before treatment, the LVEDV, LVESV, LVEF and E/A between the two options were statistically insignificant (P gt; 0.05). After treatment, these indexes of Ⅱ group were improved significantly compared with Ⅰ group, with established statistics (P lt; 0.05). Conclusion: The treatment with bisoprolol fumarate for elderly patients with hypertension and cardiac insufficiency can improve heart function, blood pressure, and it is worth recommending. 【Keywords】Hypertension; cardiac insufficiency; bisoprolol fumarate; clinical value 【中图分类号】R544.1 【文献标识码】A 【文章编号】2096-0867（2016）13-138-02 在老年高血压病患者的合并症中，心功能不全（CHF）属于其中较常见也较严重的一种。beta;-受体阻滞剂是近年临床广泛应用的一类心血管活性药物，在调节心脏功能、改善心肌血液循环、预防致命性心律失常等方面均有显著效果，现已被广泛用于多种心血管病的治疗，但对于老年高血压病伴CHF的治疗，目前仍较少报道。本文中，我院尝试采取富马酸比索洛尔片对该病患者进行对照治疗与讨论，试