尿沉渣分析仪与尿培养联合检测对于尿路感染的检验意义.docVIP

精品论文 参考文献 尿沉渣分析仪与尿培养联合检测对于尿路感染的检验意义 郑慧娟1、2 鲍玉洲3 （1郑州大学基础医学院研究生学位班 450001） （2郑州大学人民医院检验科 450003） （3郑州大学人民医院河南省眼科研究所 450003） 【摘要】目的 对比分析尿沉渣分析仪与尿培养在尿路感染（UTD）诊断方面的意义，并观察引起本院尿路感染的常见病原菌的分布特点及耐药性，为临床合理选用抗菌药物提供依据。方法　对256例疑似尿路感染患者的中段尿标本分别进行尿沉渣和尿培养检测，并对培养结果进行药敏试验。结果　256例样本中尿路感染的真阳性率和真阴性率分别为82.5%、100%、73.9%、80.4%(chi;2=0.242,Pgt;0.05)；阳性预测值和阴性预测值分别为68.0%、74.4%、86.3%、100%(chi;2=0.066,Pgt;0.05)；准确度分别为77.3%、87.5%。尿培养革兰阴性杆菌占73.12%，其中大肠埃希菌占居首位，革兰阳性球菌占23.66%，其中肠球菌属占首位，真菌占3.23%。结论　尿沉渣分析仪在尿路感染诊断中具有快捷、方便的特点，临床效能接近尿培养，但没有尿培养好。建议在临床应用中，可联合同时使用两种方法，达到更快捷、准确的诊断结果，以提高尿路感染的检出率。大肠埃希菌为主的革兰阴性杆菌是尿路感染的主要病原菌，肠球菌属其次，多重耐药菌逐年增加，要根据药敏结果更加合理、谨慎地用药。 【关键词】 尿路感染 尿培养 尿沉渣分析仪 耐药性 【中图分类号】R446.12 【文献标识码】A 【文章编号】2095-1752（2013）28-0142-02 Inspection significance of combination application of urinary sediment analyzer and urinary culture in diagnosis of urinary tract infection 【Abstract】 Objective:To investigate the significance of the urinary sediment analyzer and urine culture in diagnosis of urinary infection.And to analyze the distribution of pathogens and antibiotic of urinary tract infection in our hospital. Methods:256 urine samples collected from patients of suspected urinary infection were tested by urinary sediment analyzer and urine culture respectively.Pathogens isolated were identified by VITEK automated microbial system.Result:The true positive rates and true negative rates of urinary sediment analyzer and urine culture were 82.5%,100%,73.9%,80.4%(chi;2=0.242,Pgt;0.05).The positive predictive value and negative predictive value were 68.0%、74.4%、86.3%、100%(chi;2=0.066,Pgt;0.05)。The accurante rates of both methods were 77.3% and 87.5%.Gram negative bacilli were accounted for 73.12% in urine culture (E.coli is the main pathogen),gram positive cocci were accounted for 23.66%,and fungi accounted for 3.23%.Conclusion:The urinary sediment analyzer is fast and convenient in diagnosis of urinary infection.Both methods have similar diagnost