Cancer Vaccines Clinical Applications Peptides and Protein英文电子书.pdfVIP

18.3: Cancer Vaccines: Clinical Applications: Peptides and Protein Vaccines Peptide Presentation on Major Histocompatibility Complex Molecules The T-cell receptor on lymphocytes with antitumor activity recognize a unique conformation on the tumor cell surface comprised of a peptide nestled in the groove of a surface major + histocompatibility complex (MHC) molecule (1,2). CD8 T cells recognize peptides attached to class I molecules, and CD4 cells recognize peptides attache