探讨支气管肺泡灌洗大剂量氨溴索治疗急性肺脓肿的临床效果.docVIP

精品论文 参考文献 探讨支气管肺泡灌洗大剂量氨溴索治疗急性肺脓肿的临床效果 黑龙江省嫩江县伊拉哈镇中心卫生院 161437 【摘 要】目的 研究分析支气管肺泡灌洗大剂量氨溴索治疗急性肺脓肿的效果。方法 此次研究的对象是选择我院2011年1月～2014年1月收治的急性肺脓肿患者120例，将其临床资料进行回顾性分析，并按随机数字表法分为大剂量氨溴索灌洗60例（治疗组）和生理盐水灌洗60例（对照组），两组均每周灌洗2次，疗程2～4周，于治疗后4周复查胸部CT。结果 治疗组治愈率为95%，明显高于对照组治愈率40%，治疗组灌洗次数[（4.3plusmn;1.3）次]较对照组灌洗次数[（5.4plusmn;1.4）次]明显减少，治疗组抗菌药疗程[（16.2plusmn;2.7）d]较对照组抗菌药疗程[（24.8plusmn;3.1）d]明显缩短，治疗组住院时间[（17.8plusmn;4.3）d]较对照组住院时间[（25.3plusmn;3.5）d]明显缩短，差异有高度统计学意义（P lt; 0.01）。结论 支气管肺泡灌洗大剂量氨溴索治疗急性肺脓肿是一种很好的治疗手段。 　　【关键词】支气管肺泡灌洗；氨溴索；急性肺脓肿；治疗 　　[Abstract] Objective To study the analysis of bronchoalveolar lavage in large doses of ambroxol in the treatment of acute pulmonary abscess effect. The object of this study is the method of our hospital from January 2011 to January 2014 were in patients with acute pulmonary abscess in 120 cases，the clinical data were retrospectively analyzed，and randomly divided into 60 cases of high dose ambroxol lavage （treatment group） and 60 cases of normal saline lavage （control group），two groups a week lavage 2 times，for 2 to 4 weeks，4 weeks after the treatment by chest CT. Results the cure rate of treatment group was 95%，significantly higher than the control group the cure rate was 40%，the treatment group lavage （4.3 + 1.3） [number] times compared with the control group，lavage （5.4 + 1.4） times [times] treatment group significantly reduced antibiotic treatment [（16.2 + 2.7） d] compared with the control group，antibiotic treatment [（24.8 + 3.1） d] significantly shorten the hospitalization time，the treatment group [（17.8 + 4.3） d] compared with the control group，the hospitalization time [（25.3 + 3.5） d] decreased significantly，the difference was statistically significant （P lt; 0.01）. Conclusion bronchoalveolar lavage of large dose of ambroxol hydrochloride in treatment of acute lung abscess is a good treatment method. [Key words] bronchoalveolar lavage；ambroxol；acute lung abscess；treatment 急性肺脓肿是呼吸内科常见难治疾病之一，是由致病微生物引起肺化脓性感染而致肺组织坏死形成的脓腔，治疗较为棘手，传统的治疗方法是静脉