糠醛改性o-季铵化壳聚糖衍生物的合成及其抗菌性能研究开发.pdfVIP

966 CHEMICAL INDUSTRY AND ENGINEERING PROGRESS 2014 33 4 O- 361021 O-O--N- O--N-FTIR1H NMREATG O--N- S.aureus E. coli pH 5.5 pH 7.2O--N-O--N-O- -N- O-- O 636.1 A 100066132014 DOI 10.3969/j.issn.1000-6613.2014.04.030 Synthesis and antibacterial properties of furfural modified chitosan derivatives LI Wei LI Mingchun XIN Meihua College of Material Science and EngineeringHuaqiao UniversityEngineering Research Center of Environment-Friendly Functional MaterialsMinistry of EducationXiamen 361021FujianChina Abstract Shiff bases and derivates of O-quaternized-N-furan methylene chitosan were synthesized by water-soluble O-quaternized chitosan and furfural. The products were characterized by FTIR1H NMR EA(elemental analysis) TG(thermogravimetric analysis) respectively. The minimum inhibitory concentration and the bacteriostasis rate of the obtained chitosan derivatives were testedand compared with those of the O-quaternized-N-benzylidene chitosan shiff base. The results showed that the antibacterial effect of series products against gram positive bacteria S. aureus was stronger than that against gram negative bacteria E. coli . The antibacterial effect the under condition at pH=5.5 was stronger than that at pH=7.2. The order of antibacterial effect was as following O-quaternized-N- furan methylene chitosanO-quaternized-N-furan methylene chitosan shiff baseO-quaternized-N-benzylidene chitosan shiff base O-quaternized chitosan. The results indicated that the antibacterial activity of chitosan derivatives with furan heterocyclic groups was obvi