探讨血清胱抑素C在糖尿病肾功能检测中的意义.docVIP

精品论文 参考文献 探讨血清胱抑素C在糖尿病肾功能检测中的意义 黑龙江省森工总医院检验科 150040 摘要：目的 浅析血清胱抑素C（CysC）在糖尿病肾功能检测中的重要意义。方法 此次研究的对象是选取我院46例糖尿病肾脏损伤患者，将其临床资料进行回顾性分析，并作为观察组，同时选取同一时间段内46例健康体检者为对照组研究对象，血清中CysC水平检测采用终点散射比浊法，同时采用本院常规血液检测方法检测所有研究对象血肌酐和尿素氮水平。结果 观察组患者CysC、血肌酐及尿素氮水平均明显高于对照组患者，差异显著，具有统计学意义（Plt;0.01）；观察组患者3项指标检测比较，CysC阳性检出率最高，为83.48%（43/46），CysC阳性检出率与血肌酐和尿素氮水平检测阳性检出率比较，差异显著，具有统计学意义（Plt;0.01）；血肌酐和尿素氮水平检测阳性检出率比较，差异无统计学意义（Pgt;0.01）。结论 CysC作为糖尿病肾脏损伤的检测指标，在糖尿病肾脏损伤早期诊断上具有重要的意义，可在临床中广泛应用推广。 　　关键词：糖尿病；肾脏损伤；血清胱抑素C；肾功能；诊断 　　Abstract：Objective To analyze the serum cystatin C（CysC）is important in the detection of renal function in diabetes mellitus. Method the study objects are selected in our hospital in 46 cases of renal injury in diabetes patients，their clinical data were retrospective analysis，and served as the observation group，and select the same time period of 46 healthy persons as the subjects of the control group，the serum levels of CysC detection the end-point scatter turbidimetry. At the same time，the hospital，routine blood test for all studied serum creatinine and blood urea nitrogen levels. Results in the observation group patients CysC，serum creatinine and blood urea nitrogen water average was significantly higher than that of the patients in the control group，significant difference has statistical significance（P lt; 0.01）；observation group patients in detection of three indexes，CysC positive rate was the highest，was 83.48%（accomplished），CysC positive rate and serum creatinine and urea nitrogen level detection positive rate comparison，significant differences，with statistical significance（P lt; 0.01）；blood urea nitrogen and creatinine levels were detected positive rate comparison，the difference was not statistically significant（P lt; 0.01）. Conclusion CysC has important significance in the early diagnosis of diabetic renal injury，and it can be widely used in clinical practice. Key words：diabetes mellitus；kidney injury；serum cystatin C；renal function；diagnosis 糖尿病（diabetes mell