改良与传统全视网膜光凝术治疗糖尿病视网膜病变疗效观察.docVIP

改良与传统全视网膜光凝术治疗糖尿病视网膜病变疗效观察 许艳 姚晶磊 陈冬梅 高鑫 北京市门头沟区医院眼科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的 比较改良全视网膜光凝术 (modified panretinal photocoagulation, MPRP) 和传统全视网膜光凝术 (panretinal photocoagulation, PRP) 治疗糖尿病视网膜病变的疗效及安全性。方法 采用临床病例对照研究方法。对2013年10月至2017年1月在我院眼科经眼底荧光素血管造影等检查确诊为重度非增殖型糖尿病视网膜病变 (severe nonproliferative diabetic retinopathy, NPDR) 或轻度增殖型糖尿病视网膜病变 (proliferative diabetic retinopathy, PDR) 并行全视网膜光凝术的患者53例 (106眼) 进行研究, 入组患者双眼糖尿病视网膜病变程度一致, 均选择右眼为治疗组, 行MPRP;左眼为对照组, 行PRP;每组53眼。激光治疗后1 d、1周、1个月、3个月、6个月观察视力、眼压、散瞳彩色眼底照相及光学相干断层扫描, 激光治疗后3个月、6个月时增加FFA检查, 比较两组疗效及安全性。结果 两组患眼经治疗后, 各时期最佳矫正视力比较差异均无统计学意义 (均为P0.05) , 但治疗组视力平均值均高于对照组。治疗组视网膜无灌注区消失、新生血管消退39眼 (73.6%) , 有效率90.6%;对照组视网膜无灌注区消失、新生血管消退29眼 (54.7%) , 有效率75.5%。两组新生血管消退率及有效率差异均有统计学意义 (均为P0.05) 。结论 MPRP治疗糖尿病视网膜病变安全有效, 疗效优于传统PRP。 关键词： 糖尿病视网膜病变; 视网膜光凝术; 无灌注区; 新生血管; 作者简介：许艳, 女, 1985年10月出生, 安徽合肥人, 硕士。联系电话 E-mail:xyanhui7956640@163.com;ORCID:0000-0002-5603-618X 收稿日期：2017-08-15 Comparison of the outcomes of modified and traditional panretinal photocoagulation for the treatment of diabetic retinopathy XU Yan YAO Jing-Lei CHEN Dong-Mei GAO Xin Department of Ophthalmology, Mentougou Hospital of Beijing; Abstract： Objective To compare the efficacy and safety of modified panretinal photocoagulation ( MPRP) and traditional panretinal photocoagulation ( PRP) for diabetic retinopathy ( DR) . Methods The clinical case-control methods were used. A total of 53 patients ( 106 eyes) who were confirmed as severe nonproliferative diabetic retinopathy ( NPDR) or mild proliferative diabetic retinopathy ( PDR) after fundus fluorescein angiography ( FFA) between October2013 to January 2017 were enrolled in this study, and the two eyes of each patients were in the same degree of DR, with the 53 right eyes undergoing MPRP ( treatment group) and the 53 left eyes receiving PRP ( control group) . Various including visual acuity, intraocular pressure, mydriatic fundus photography and optical co