不同手术麻醉方式对梦发生的影响.docVIP

不同气管导管润滑剂对全身麻醉患者术后咽喉痛的影响 刘海恋 黄绍强 王美华( 作者单位：200090 上海，复旦大学附属妇产科医院麻醉科 通信作者：黄绍强，电子邮箱为timrobbins71@163.com 【摘要】目的 探讨不同润滑剂润滑气管导管对全身麻醉患者术后咽喉痛的影响。方法 本研究为前瞻性的随机、双盲、对照研究，选择150例择期在气管插管全身麻醉下行妇科腹腔镜手术的患者，年龄20～60岁，美国麻醉医师学会（American Society of Anaesthesiologists，ASA）分级Ⅰ或Ⅱ级，手术时间1～3 h。麻醉前按照随机数字表法分组，将一次性气管导管头端分别涂以0.9%氯化钠溶液、石蜡油或1%丁卡因凝胶，实施标准的全身麻醉和镇痛方案。于拔管后10 min、术后1 h、术后24 h由不知道分组情况的观察者记录患者咽喉痛和术后声音嘶哑的发生情况。结果 丁卡因凝胶组术后各时间点的咽喉痛发生率和严重程度均显著低于0.9%氯化钠溶液组和石蜡油组（P值均0.05），而0.9%氯化钠溶液组与石蜡油间的差异均无统计学意义（P值均0.05）。3组间术后1 h声音嘶哑发生率的差异无统计学意义（P=0.136），术后24 h时3组均无声音嘶哑的病例。结论 与0.9%氯化钠溶液和石蜡油相比，以丁卡因凝胶润滑气管导管可以明显降低气管插管全身麻醉术后咽喉痛的发生率和严重程度。 【关键词】气管插管；咽喉疼痛；丁卡因 Comparison between saline, paraffin oil and tetracaine jelly applied over tracheal tube to reduce postoperative sore throat LIU Hailian, HUANG Shaoqiang, Wang Meihua. Department of Anesthesiology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200090, China Corresponding author: HUANG Shaoqiang. E-mail: timrobbins71@163.com 【Abstract】Objective To investigate the effects of different lubricants applied over tracheal tube on postoperative sore throat after general anesthesia. Methods This prospective, double-blind, randomized-controlled study was conducted in 150 women, aged between 20 and 60 yr, ASA physical status class I or II, scheduled for elective gynecological laparoscopic surgery (likely to last between 1 and 3 h) under standard general anaesthesia and analgesia. The patients were randomized into three groups using a computer-generated randomization list. Sterilizing saline, paraffin oil or tetracaine jelly were applyed respectively on the disposable tracheal tube before anaesthesia. A blinded observer interviewed all patients on postoperative sore throat and hoarseness of voice at 10 min, 1 h and 24 h after operation. Results The incidences of postoperative sore throat were significantly lower in the tetracaine group compared with the other two groups at any evaluation time (P0.05), while these did not differ between the salin