有关传染性单核细胞增多症发生肾损害的危险因素与预后的随访.docVIP

精品论文 参考文献 有关传染性单核细胞增多症发生肾损害的危险因素与预后的随访 严建华 　　（广东省惠州市中心人民医院儿科 516001） 　　【摘要】目的 探讨有关传染性单核细胞增多症发生肾损害的危险因素, 探讨预防肾损害的方法。方法 回顾性分析我院46例儿童传染性单核细胞增多症伴肾损害患儿的资料, 并随机抽选该病未发生肾损害的患儿资料46例进行对比分析。结果 本次观察中，肾损害组年龄在3～ 7 岁段肾损害发生率为45.65%（21/46），男性患儿肾损害发生率76.09%（35/46），病程(7.6plusmn;3.1) d、发热时间(9.1plusmn;3.6)d，重症率为60.87%（28/46），均高于非肾损害组数据。全部患者随访一个月，均预后良好。结论 传染性单核细胞增多症发生肾损害的危险因素与年龄、性别、病程、发热时间及病情程度相关。 　　【关键词】传染性单核细胞增多症 肾损害 危险因素 　　【中图??类号】R51 【文献标识码】A 【文章编号】2095-1752（2014）20-0057-02 　　Related Risk Factors of Renal Damage Caused by Infectious Mononucleosis and Follow-Up Visit of Prognosis 　　【Abstract】 Objective: To discuss the related risk factors of renal damage caused by infectious mononucleosis and preventive methods of renal damage. Method: Clinical data of 46 children with renal damage caused by infectious mononucleosis were analyzed retrospectively and 46 children without renal damage were randomly chosen for comparison. Result: In the observation, occurrence rate of renal damage of 3～7 year old children of rental damage group was 45.65% (21/46), occurrence rate of renal damage of male children was 76.09% (35/46), course of disease was (7.6plusmn;3.1) d, fever lasting time (9.1plusmn;3.6)d, severe case rate 60.87% (28/46), all higher than non-renal damage group. All patients were given one month follow-up visit and their prognosis was all good. Conclusion: Risk factors of renal damage caused by infectious mononucleosis were related with age, gender, course of disease, fever lasting time and disease severity. 　　【Key words】Infectious Mononucleosis Renal Damage Risk Factors 　　传染性单核细胞增多症(IM)是由（Epstein-Barr virus ，EBV)引起的，虽为自限性疾病，但因其病毒血症可扩散到全身各系统，故几乎可累及所有的组织器官，尤以肾脏损害较为常见[1-2]。患者常见肾脏损害 尤其是亚临床肾受累 表现为尿少 浮肿及肾早期损伤指标异常 但尿常规及尿沉渣镜检正常。本文回顾性分析了我院儿科接收的92例传染性单核细胞增多症患儿临床资料，通过对比分析不同组别间发生肾损害差异，评估危险因素并进行预后随访，现报道如下。 　　1 临床资料 　　1.1 一般资料 　　本院2010年11月～2013年11月共收治了150例传染性单核细胞增多症的患儿,回顾性分析其中有46例儿童IM伴肾损害，并从余下的患儿资料中随机抽选该病未发生肾损害的患儿资料46例，分为IM肾损伤组和非肾