浅析综合干预预防与控制梅毒母婴传播的临床意义.docVIP

精品论文 参考文献 浅析综合干预预防与控制梅毒母婴传播的临床意义 黑河市爱辉区张地营子乡卫生院 164354 【摘 要】目的：研究探讨综合干预阻断梅毒母婴传播的效果和意义。方法：此次研究的对象是选择2009年1月～2011年5月我院就诊的妊娠梅毒患者共85例，将其临床资料进行回顾性分析，其中51例患者的配偶能够接受综合干预和正规治疗，被我们列为观察组；而在临床接诊中34例患者未能及时治疗和干预就分娩的梅毒产妇及婴儿，被列为对照组。结果：综合干预治疗组胎传梅毒发生率对比，未治疗组明显高于综合干预组（Plt;0.05）；经治疗观察，在孕34周以后接受治疗者。胎儿将有50％～70％的机会感染梅毒，未经治疗孕妇98.9%通过胎盘将病原体垂直传给胎儿。结论：对孕产妇进行早期梅毒检测，可以阻断母婴垂直传播，从而降低婴儿被感染梅毒的机会，减少围产儿死亡率，具有重要的临床意义。 【关键词】预防；控制；梅毒；母婴传播 Abstract：Objective：To study the effect and significance of comprehensive intervention to block the mother to child transmission of syphilis.Methods：the object of the study is a total of 85 cases of January 2009 to may 2011 in our hospital for treatment of pregnant syphilis patients，the clinical data were retrospectively analyzed，which spouses of 51 patients can accept comprehensive intervention and regular treatment，we listed as the observation group；and in clinical admissions in 34 patients failed to timely treatment and intervention delivery of syphilis in pregnant women and infants，were classified as control group.Results：the incidence rate of syphilis in the treatment group was significantly higher than that in the untreated group，which was significantly higher than that in the comprehensive intervention group（Plt;0.05）.After treatment，the patients in the treatment group received the treatment after 34 weeks of pregnancy.The fetus will have 50% to 70% of the chance of infection of syphilis，without treatment of 98.9% pregnant women through the placenta will be transmitted to the fetus through the placenta.Conclusion：the detection of early syphilis in pregnant women can block the vertical transmission of the mother and infant，thus reducing the chance of infant being infected with syphilis，reducing the perinatal mortality，and has important clinical significance. Key words：prevention；control；syphilis；mother infant transmission 我国梅毒流行形势目前已十分严峻，在各性传播疾病中，梅毒的危害性仅次于艾滋病，已成为我国乃至全球的严重的公共卫生问题，并开始不断引起世界卫生组织的关注。我国胎传梅毒的年发病率增长速度近年来呈逐年上升趋势，研究证实，梅毒孕妇的不良妊娠结局是非梅毒孕妇的12倍[1]。阻