溃疡性结肠炎活动期中药灌肠联合肠道生物制剂的应用价值研究.docVIP

精品论文 参考文献 溃疡性结肠炎活动期中药灌肠联合肠道生物制剂的应用价值研究 蒋纯 马一丹 　　（四川南充市中心医院 四川 南充 637000） 　　【摘 要】目的：研究中药灌肠联合肠道生物制剂治疗活动期溃疡性结肠炎的临床应用价值。方法：选取我院活动期溃疡性结肠炎患者100例，将其随机分为治疗组和对照组各50例，对照组给予美沙拉嗪肠溶片口服，治疗组采用中药灌肠联合肠道生物制剂布拉氏酵母菌活菌散剂，治疗3个疗程后，对比分析两组患者治疗效果。结果：治疗组总有效显著优于对照组（Plt;0.05）；6个月内复发情况显著低于对照组 (Plt;0.05)；两组治疗后，治疗组的免疫水平改善情况明显优于对照组（Plt;0.05）。结论：中药灌肠联合肠道生物制剂治疗活动期溃疡性结肠炎患者，可显著改善肠道免疫情况，提高临床疗效，降低复发率。 　　【关键词】溃疡性结肠炎；中药灌肠；肠道生物制剂 　　【中图分类号】R574.62 【文献标识码】B 【文章编号】1003-5028（2015）8-0431-01 　　【Abstract】Objective: To study the traditional Chinese medicine enema with intestinal biological preparation for treating ulcerative colitis clinical application value. Methods: A total of 100 patients with active ulcerative colitis patients in our hospital, which were randomly divided into treatment group and control group with 50 cases in each group, the control group was given Mesalazin Enteric-coated Tablets oral, treatment group were treated with traditional Chinese medicine enema with intestinal bacteria biological preparation of Saccharomyces boulardii powder, after 3 courses of treatment, the therapeutic effect of two groups were compared and analyzed. Results: The treatment group the total efficiency was significantly better than the control group (Plt;0.05); recurrence within 6 months was significantly lower than the control group (Plt;0.05); the two groups after treatment in treatment group, the immunity level of improved significantly better than the control group (Plt;0.05)Conclusion:Traditional Chinese medicine enema combined with intestinal biological preparation for treating ulcerative colitis, can significantly improve the intestinal immunity, improve clinical curative effect, reduce the recurrence rate. 　　【keywords】ulcerative colitis; Traditional Chinese medicine enema; intestinal biological preparation 　　溃疡性结肠炎是一种直肠和结肠慢性非特异性炎症性疾病，临床上以腹泻、腹痛、黏液脓血便及里急后重为特征性表现，多为活动期与缓解期交替而呈慢性过程[1]。本科于选取收治我院的活动期溃疡性结肠炎患者100例，对其中50例采用中药灌肠联合肠道生物制剂进行治疗，取得较好效果，现报告如下。 　　1 资料与方法 　　1.1 一般资料 100例病例均来自于2012年2月-2014年2月收治于我院的活