瑞芬太尼全身麻醉对老年胃癌患者术后认知功能障碍的影响.docVIP

精品论文 参考文献 瑞芬太尼全身麻醉对老年胃癌患者术后认知功能障碍的影响 湖南省安仁县人民医院 湖南郴州 423600 摘要：目的：观察分析瑞芬太尼全身麻醉对老年胃癌患者术后认知功能产生的影响。方法：选择2012年11月-2014年1月来我院实施胃癌根治术的90例老年患者作为研究对象，基于麻醉药物的不同将其分为试验组与对照组，试验组45例患者采用瑞芬太尼实施全身麻醉，对照组45例患者采用芬太尼实施全身麻醉，借助于精神状态量表（MMSE）分别于术前和术后对患者认知功能进行评估，同时记录两组患者术后语言应答时间、睁眼时间以及拔管时间，比较术后认知功能障碍发生率。结果：两组患者术前 MMSE评分无显著差异，无统计学意义（P＞0.05）；术后两组患者MMSE评分差异明显，试验组术后认知功能障碍发生率明显低于对照组，且睁眼时间、语言应答时间以及拔管时间也明显比对照组短，组间差异明显，有统计学意义（P＜0.05）。结论：通过本次研究结果的分析可知，在老年胃癌手术中采用瑞芬太尼实施全身麻醉有利于患者术后认知功能早期恢复，降低认知功能障碍发生率，在临床中值得应用和推广。 关键词：认知功能；瑞芬太尼；障碍；胃癌；全身麻醉 【 abstract 】 objective：to observe the analysis，fentanyl general anesthesia on postoperative cognitive function in elderly patients with gastric cancer.Methods：in November 2012 - January 2014 to our hospital implementation of 90 cases of elderly patients with gastric cancer radical as the research object，based on its different anesthetic divided into trial group and control group，experimental group 45 cases were treated by fentanyl implementation of general anesthesia，control group 45 cases were treated by fentanyl implement general anesthesia，with the aid of mental state scale（MMSE）in patients with preoperative and postoperative cognitive function assessment，at the same time two groups of patients with postoperative language response time，open time and extubation time，compare the incidence of postoperative cognitive dysfunction.Results：two groups of patients with preoperative MMSE score had no significant difference，there is no statistical significance（P gt; 0.05）；Two groups of patients with postoperative MMSE score difference obvious，experimental group obviously lower than the control group，the incidence of postoperative cognitive dysfunction and open time，language，response time and extubation time is shorter than the control group obviously，clear difference between groups was statistically significant（P lt; 0.05）.Conclusion：through the analysis of the results of this study shows that in elderly gastric cancer surgery using fentanyl implementation of postoperati