益气活血中药预防骨科大手术后深静脉血栓的临床观察.docVIP

精品论文 参考文献 益气活血中药预防骨科大手术后深静脉血栓的临床观察 中国中医科学院望京医院骨关节二科 北京 100102 【摘 要】目的 探讨使用中药预防骨科大手术后深静脉血栓的可行性。方法 将70例在我科进行的人工膝、髋关节置换及髋部骨折内固定的患者随机分为中药组35例、对照组35例。中药组术后使用中药预防血栓，对照组术后使用低分子肝素钙抗凝。术后第2天和第8天进行凝血4项、D－二聚体（D－dimer）和下肢彩超等检查，选取其中的纤维蛋白原（FIB）、凝血酶原时间（PT）、部分凝血酶原时间（APTT）和D-dimer进行用药前后比较。并通过临床检查和下肢彩超判断有无血栓形成。结果 对照组术后1例患者发生下肢深静脉血栓；2组PT均较本组用药前下降（Plt;0.05）；中药组D-dimer较本组用药前下降（Plt;0.05）。结论 单纯应用中药预防骨科大手术后的深静脉血栓有一定可行性。 【关键词】中药；益气活血；深静脉血栓；预防 【中图分类号】R269【文献标识码】A【文章编号】2096-0867（2016）-09-019-02 Clinical observation of preventing deep vein thrombosis post major orthopedic surgery with Chinese herb. Abstract Objective To probe the availability in preventing the deep vein thrombosis （DVT）post major orthopedic surgery with Chinese herb. Methods From January 2007 to August 2008，seventy patients who were treated with total knee or hip joint replacement or hip fracture internal-fixation were divided into two groups randomly：treatment group（35cases），control group（35cases）. In treatment group ，only herbs was used post surgery；while low-molecular-weight heparins calcium（LMWH）was used in control group. Coagulation test，D-dimer test and color-ultra-sound were respectively done 2rd day and 8th day post surgery，and compare the FIB，PT，APTT and D-dimer respectively pre or post treatment. got a diagnosis of DVT through clinical examination and color-ultra-sound. Results Only one case（control group）of DVT in all；the average value of D-dimer in two groups were both drop， the treatment group had significant difference（plt;0.05）with the treatment，while control group had no significant difference（pgt;0.05）. the average value of PT in two groups were both drop，two group had significant difference（plt;0.05）with the treatment both. The APTT and FIB comparison had no significant difference（pgt;0.05）both in two groups；all the parameter difference had no significant difference（pgt;0.05）between two groups. Conclusion Chinese herb could independently prevent deep vein thrombosis post major orthopedic surge