盐酸左西替利嗪联合雷尼替丁、润燥止痒胶囊治疗慢性荨麻疹的疗效观察.docVIP

精品论文 参考文献 盐酸左西替利嗪联合雷尼替丁、润燥止痒胶囊治疗慢性荨麻疹的疗效观察 王淑贞（库尔勒市第二人民医院 新疆库尔勒 841000） 【中图分类号】R969【文献标识码】A【文章编号】1672-5085（2012）16-0050-02 【摘要】目的 观察盐酸左西替利嗪联合雷尼替丁、润燥止痒胶囊治疗慢性荨麻疹的疗效和安全性。方法 84例慢性荨麻疹患者随机分为治疗组和 对照组，治疗组和对照组均口服盐酸左西替利嗪片5mg,每日1次，连续服用4w，治疗组加服雷尼替丁胶囊150mg，每日两次连续服用4w;润燥止痒胶囊2g，每日3次,连续服用4w。结果 治疗1w后，治疗组和对照组的有效率分别为72.09%和65.85%，治疗组疗效明显优于对照组：治疗2w后，两组有效率分别为86.05%和73.17%，两组有显著差异；治疗4w后两组有效率分别为93.02%和82.93%，两组有显著性差异，两组均未发现严重的药物不良反应。结论 盐酸左西替利嗪联合雷尼替丁、润燥止痒胶囊治疗慢性荨麻疹疗效显著，安全性好。 【关键词】盐酸左西替利嗪片 雷尼替丁胶囊 润燥止痒胶囊 慢性荨麻疹 The chlorhydric acid left cetirizine combined with ranitidine, Runzao Zhiyang Capsule in treatment of chronic urticaria 【Abstract】 Objective: To observe the chlorhydric acid left cetirizine combined with ranitidine, Runzao Zhiyang Capsule in the treatment of chronic urticaria efficacy and safety. Methods: 84 cases of chronic urticaria patients were randomly divided into treatment group and control group, the treatment group and the control group were treated with oral cetirizine hydrochloride left 5mg, 1 times daily, continuous take 4w, The treatment group plus ranitidine capsules two times daily for taking 150mg, 4W; 2G Runzao Zhiyang Capsule, 3 times daily, continuous take 4w. Results：one weed later, the treatment group and the control group with efficiencies were respectively 72.09% and 65.85%, the curative effect in treatment group was significantly better than the control group after treatment: 2W, two groups have efficiencies were respectively 86.05% and 73.17%, two groups have significant differences; treatment of 4W after two rate in the group were 93.02% and 82.93%, two groups had significant differences between the two groups were not found, serious adverse drug reaction. Conclusion: the chlorhydric acid left cetirizine combined with ranitidine, Runzao Zhiyang Capsule in the treatment of chronic urticaria with remarkable curative effect, good safety. 【Key words】left cetirizine hydrochloride ranitidine capsules; Runzao Zhiyang Capsule chronic urticaria 自2010年6月