盐酸胺碘酮联合步长稳心颗粒治疗阵发性快速房颤疗效观察.docVIP

精品论文 参考文献 盐酸胺碘酮联合步长稳心颗粒治疗阵发性快速房颤疗效观察 严新美(江西新余市人民医院心血管内科 江西新余 338000） 【中图分类号】R541.7+5 【文献标识码】A【文章编号】1672-5085（2013）27-0168-01 【摘要】 目的:评价胺碘酮联合步长稳心颗粒治疗阵发性快速房颤的疗效。方法 将80例阵发性快速房颤患者随机分为治疗组和对照组，两组均予以吸氧、心电监护、胺碘酮治疗，治疗组加服步长稳心颗粒，共观察6个月。结果 观察6个月后，治疗组在有效改善症状、复律时间、及胺碘酮用量方面明显优于对照组，差异有统计学意义（Plt;0.01）。结论 胺碘酮与步长稳心颗粒合用治疗阵发性房颤，能有效改善症状，提高治疗效果且可减少胺碘酮用量，缩短复律时间，有一定的临床应用价值。 【关键词】盐酸胺碘酮 步长稳心颗粒 治疗 阵发性快速房颤 The Clinical Observation of amiodarone with Wenxinkeli in Treatment of rapid atrial fibrillation in patients with paroxysmal efficacy Yan Xinmei.Department of Internal Medicine,JiangXi Xinyu hospital.Xinyu 338000 【Abstract】 Objective Evaluation of amiodarone the joint step Wenxinkeli rapid atrial fibrillation in patients with paroxysmal efficacy. Methods 80 patients with paroxysmal rapid atrial fibrillation were randomly divided into a treatment group and a control group, and both groups are oxygen, ECG, amiodarone,The treatment group took Buchangwenxin particles were observed 6 months. Results Observed after 6 months, the treatment group was effective in improving symptoms, time of cardioversion and amiodarone dosage was significantly better than the control group, the difference was statistically significant (P lt;0.01). Conclusion the particle combination therapy of paroxysmal atrial fibrillation, amiodarone and Buchangwenxin improve symptoms, improve treatment and reduce amiodarone dosage and shorten the time of cardioversion clinical application value. 【Key words】 Amiodarone Wenxinkeli Treat Paroxysmal rapid atrial fibrillation 1 资料与方法 1.1病例选择 选择标准：阵发性房颤患者80例，发作时心室率gt;120次/分，自觉症状表现为心悸、胸闷、头昏、乏力。随机分为治疗组40例，男30例，女10例，年龄56-76，平均66plusmn;2.2岁，原发病为冠心病25例，高心病10例，风心病5例。对照组40例，男28例，女12例，年龄54-75岁，平均65.5plusmn;2.3岁，原发病为冠心病22例，高心病15例，风心病3例。两组一般资料差异无统计学意义，具有可比性。 1.2 治疗方法 两组均予以吸氧、心电监护、胺碘酮150mg于10min内静脉注射，之后口服胺碘酮，第一周600mg/d,第二周减至400mg/d,第三周减至200mg/d,持续至试验结束或房颤复发。 治疗组加服步长稳心颗粒每次9g,每日3次，疗程6个月。每位患者半个月电话随访1次，每个月门诊随访1次，每三个月做胸片和肝功能检查。治疗期间有3例退出