《中外医疗》杂志社病毒性心肌炎临床疗效探讨_刘晔.pdf.docVIP

中外医疗 2015 NO.30 China Foreign Medical Treatment 论 著 病毒性心肌炎临床疗效探讨 刘晔 吉林省人民医院心内科,吉林长春 130021 [摘要] 目的 探究应用磷酸肌酸治疗病毒性心肌炎的临床疗效。 方法 整群选取 2014 年 4 月—2015 年 4 月来该院入 住的患者 158 例，所有患者均被确诊为病毒性心肌炎。 随机将患者分为对照组和观察组。 两组成员均为 79 例。 给予 对照组常规治疗方案，给予观察组磷酸肌酸联合基础治疗，检测两组患者治疗前后的磷酸激酶同工酶含量、心电图变 化及不良反应发生的情况，判断两组患者的临床疗效。 结果 治疗后两组的磷酸激酶同工酶的含量均下降，但观察 组下降的更明显。 治疗后两组数据进行对比，差异具有统计学意义（t=10.314，P0.05）。 对照组的总有效率为 70.89%， 观察组的总有效率为 91.14%，观察组明显优于对照组，差异统计学意义（χ2=10.71，P0.05）。且观察组的不良反应更加 轻微，发生不良反应的例数也更加少。 结论 该实验方法对于改善病毒性心肌炎患者的临床症状，使各项指标恢复 正常等方面发挥了积极作用。 因此，该方法值得推广。 [关键词] 病毒性心肌炎；磷酸肌酸；干扰素 [中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2015）10（c）－0014-02 Observation on the Clinical Efficacy of the Treatment for Viral Myocarditis LIU Ye Department of Cardiology, Jilin Provincial Peoples Hospital, Changchun, Jilin Province, 130021 China [Abstracts] Objective To explore the clinical effect of creatine phosphate on viral myocarditis. Methods From April 2014 to April 2015, 158 cases confirmedly diagnosed with viral myocarditis in our hospital were selected as the subjects. The pa-tients were randomly divided into the control group and the observation group with 79 cases in each. Patients in the control group were treated by the conventional treatment, and those in the observation group were treated by creatine phosphate combined with basic treatment. The content of phosphate kinase isoenzyme and electrocardiogram were detected in both groups before and after treatment, and the incidence of adverse reactions of the two groups was observed. And the clinical efficacy of the two groups was assessed. Results The content of phosphate kinase isoenzyme decreased in both groups after treatment, moreover, that decreased more obviously in the observation group, the data of two groups were compared after treatment, the difference was statistically significant (t=10.314, P0.05). The overall effective rate of the observation group was much higher than that of the control group(91.14% vs 70.89%), the difference was statistically si