术后恶心呕吐的预防和治疗（英文）PPT.ppt

Randomized, prospective, double blind, placebo controlled, dose ranging. Two parallel studies performed. Multicenter with 20 total sites. Over 2500 total patients enrolled, 1000 patients (500 in each study) received study medication. 90% female. Standard anesthetic included barbiturate, opioid, NMB agent and reversal, nitrous and either isoflurane or enflurane. Complete response defined as no vomiting, no rescue medication. Randomized, double blind, placebo controlled, dose ranging. multicenter (25) trial. 635 females undergoing outpatient laparoscopy. Standard anesthetic including barbitu