肝病终末期模型评分动态变化联合血清钠预测肝硬化失代偿期临床应用价值.docVIP

精品论文 参考文献 肝病终末期模型评分动态变化联合血清钠预测肝硬化失代偿期临床应用价值 武汉市黄陂区人民医院感染科 湖北武汉 430300 【摘 要】目的：探讨终末期肝病模型评分动态变化联合血清钠预测肝硬化失代偿期预后的临床价值。方法：对55例住院治疗的终末期肝病患者进行回顾性分析。按入院血清钠浓度将所有患者分为两组：I组（血清钠ge;135mmol/L）29例和Ⅱ组（血清钠lt;135mmol/L）26例。根据当时及1个月后的化验结果计算Child-Pugh、MELD评分及△MELD。并随访3个月的患者生存率。结果：血清钠正常的患者Child-Pugh评分C级、MELD评分ge;20分及△MELDgt;0的病例数明显少于低钠血症患者，血清钠正常患者的Child-Pugh总体评分、MELD总体评分、△MELD均明显低于低钠血症患者。肝硬化失代偿期患者3个月病死率与△MELD有关。结论：肝硬化腹水患者出现低钠血症预示病情较重，血清钠联合△MELD更能反映肝病的严重程度。 【关键词】肝病终末期模型；评分动态变化；联合血清钠；肝硬化失代偿期 Model for end-stage liver diseases score joint on the dynamic change of serum sodium predict cirrhosis of the liver decompensation period clinical application value singh （huangpi district of wuhan city peoples hospital infection Hubei wuhan 430300） [abstract] objective：to study the model for end-stage liver disease score joint on the dynamic change of serum sodium predicts prognosis of cirrhosis of the liver decompensation period clinical value.Methods：55 cases of hospitalized patients with end-stage liver disease were retrospectively analyzed.According to the serum sodium concentration will all hospitalized patients were divided into two groups：group I（serum sodium tendency for 135 / L or higher）29 cases and Ⅱ group serum sodium（lt; 135 tendency for 26 cases/L）.According to the test results and 1 month after calculation Child - Pugh，MELD score and delta MELD.Survival of the patients were followed up for 3 months.Results：patients with normal serum sodium Child - Pugh score c-class，MELD score 20 points or more，and delta MELD cases gt; 0 is less than that of patients with hyponatremia，Child - Pugh，overall rating of patients with normal serum sodium and MELD overall score，delta MELD were significantly lower than that of patients with hyponatremia.Patients with cirrhosis of the liver decompensation period of 3 months mortality associated with delta MELD.Conclusion：the liver cirrhosis ascites patients with hyponatremia signal condition is heavier，serum sodium joint delta MELD can better reflect the s