肾小球疾病PPT.ppt

Glomerular disease;outline;Anatomy and function;Anatomy;Anatomy;;;Glomerular Anatomy;Structure of normal glomerular capillary;;;General pathogenesis;;Antibody mediated GN - Circulating Immune complex;Antibody mediated GN - In-situ Immune complex ;Antibody mediated GN - In-situ Immune complex (trapped Ag);pathogenesis;Glomerular Filtration Barrier;Glomerular Filtration Barrier Injury;Classification of Glomerular Disease;Clinical syndromes and presentation;Characteristics of Glomerular Diseases;Clinical syndromes and presentation;;Renal Biopsy Processing;Renal Biopsy Processing;Renal Biopsy Processing;Renal Biopsy Processing;Pathology;Pathological classification of GN; 增生性肾炎 proliferative glomerulone-phritis 系膜增生性肾小球肾炎 mesangial proliferative GN 毛细血管内增生性肾小球肾炎 endocapillary proliferative GN 系膜毛细血管内增生性肾小球肾炎 mesan-gial capillary GN 新月体肾炎 crecentic GN;Clinical syndromes of glomerular diseases;;;;Asymptomatic hematuria/ or proteinuriaLatent nephritis;CASE I ;HE;PAS;IgA;;;IgA Nephropathy;Clinical syndromes of glomerular diseases;Nephrotic Syndrome;Nephrotic syndrom-etiology(1);Nephrotic syndrom-etiology(2);Nephrotic syndrom-epidemiology;14 year-old, male, high-school student History: No significant medical history Fatigue x 3 weeks Edema x 1 week Physical: Mild generalized edema Urinalysis: 4? protein Many hyaline casts Few granular casts No RBCs or RBC casts Lab Data: proteinuria 4g/d , alb 20g/l,normal renal function, Hepatitis (-), Auto-immunity Ab (-) Renal biopsy;;;Electron Microscopy: effacement of foot processes;;CASE III;;CASE III;Silver;CASE III;CASE III;CASE III;;CASE II-MN;Membranous Nephropathy;;Pathogenesis/Complication;Treatment of NS;Liver;0.25mg/kg.d;0.25mg/kg.d;0.25mg/kg.d;0.25mg/kg.d;Clinical syndromes of glomerular diseases;急性肾小球肾炎 Acute GN;急性肾小球肾炎 Acute GN;急性肾小球肾炎 Acute GN;Clinical syndromes of glomerular diseases;Rapid prog