脑梗死采用不同剂量辛伐他汀治疗的临床效果与药理分析.docVIP

精品论文 参考文献 脑梗死采用不同剂量辛伐他汀治疗的临床效果与药理分析 肖琳琳 　　泸州医学院附属医院药剂科 四川泸州 646000 　　【摘 要】目的：探究脑梗死采用不同剂量辛伐他汀治疗效果和药理。方法：选取某院2013 年11 月~2014 年12 月收治的 70 例脑梗死患者，将其随机分成观察组和对照组，各35 例。观察组取双倍剂量辛伐他汀进行治疗，于患者临睡前服用30mg/d， 3 个月为一疗程。对照组取正常剂量辛伐他汀进行治疗，比较不同剂量辛伐他汀的治疗效果。结果：观察组治疗的总有效率，明 显优于对照组，差异有统计学的意义，Plt;0.05。结论：脑梗死通过双倍剂量的辛伐他汀进行治疗，治疗效果较佳，值得临床方面 应用和推广。 　　【关键词】脑梗死；不同剂量辛伐他汀；临床效果 　　Clinical effect and pharmacological analysis of different doses of simvastatin treatment for cerebral infarction Abstract：Objective：To explore the effect and pharmacology of different dosage of simvastatin in the treatment of cerebral infarction.Methods：70 patients with cerebral infarction were randomly divided into observation group and control group，35 cases in each group，cases of cerebral infarction were randomly divided into the observation group and the control group in December，November 2013.The observation group to take a double dose of simvastatin treatment，in patients before taking 30mg/d，a course of 3 months.The control group took the normal dose of simvastatin treatment，compared the treatment effect of different doses of simvastatin.Results：the total effective rate of the observation group was significantly better than the control group，the difference was statistically significant， Plt;0.05.Conclusion：the treatment of cerebral infarction by double dose of simvastatin，the treatment effect is better，it is worthy of clinical application and promotion. Key words：cerebral infarction；simvastatin；clinical effect 　　【中图分类号】R181.3+2【文献标识码】A【文章编号】2096-0867（2015）-05-012-02 　　随着社会经济不断的发展，促使我国人口逐渐向老年化发 展，而心脑血管方面的病症发病率也在不断的提升。脑梗死， 属于临床方面多发的缺血性脑血管方面的病症，主要是因为脑 血液方面的供应障碍所造成，主要的体现为缺血和缺氧[1]。现 阶段，临床方面多会通过脑灌注的方式对患者的细胞加以保 护，以及溶栓和抗凝等。降至方面的药物，主要应用于脑梗死 的治疗。而辛伐他汀属于降脂方面的药物。本次研究，选取 70 例脑梗死患者作为研究对象，探究不同剂量的辛伐他汀治 疗脑梗死的效果和药理，现进行具体的报道。 　　With the continuous development of social economy，Chinas population is gradually to the development of the elderly，while the incidence of diseases in cardiovascular and cerebrovascular diseases is also in