艾司西酞普兰合并生物反馈治疗惊恐障碍的对照研究.docVIP

精品论文 参考文献 艾司西酞普兰合并生物反馈治疗惊恐障碍的对照研究 周浩 孔令军 李龙 （江西省吉安市第三人民医院 江西吉安 343000 ） 【摘要】目的：探讨生物反馈合并艾司西酞普兰治疗惊恐障碍的临床效果。方法：将80例惊恐障碍患者随机分为两组，各40例，对照组给予艾司西酞普兰治疗，观察组在此基础上加用生物反馈治疗，对两组临床结果进行回顾性分析。结果：观察组总有效率为87.5%，对照组总有效率为70.0%，两组总有效率比较差异有统计学意义(Plt;0.05)。两组HAMA 总分在治疗前及治疗后1 周比较差异无统计学意义(Pgt;0.05)，在治疗第2 周、4 周、8 周比较差异有统计学意义(Plt;0.05 或Plt;0.01)。两组WHOQOL-100 评分在治疗前比较差异无统计学(Pgt;0.05)，两组治疗后均优于治疗前，在治疗第8 周，观察组社会关系、独立性、心理及生理评分显著高于对照组，差异有统计学意义(Plt;0.05或Plt;0.01)。两组不良反应发生率比较差异无统计学意义(Pgt;0.05)。结论：生物反馈合并艾司西酞普兰治疗惊恐障碍疗效优，患者的生活质量有明显提高。 【关键词】 惊恐障碍 生物反馈 艾司西酞普兰 社会功能 【中图分类号】R749.05 【文献标识码】A 【文章编号】2095-1752（2012）21-0386-02 Biofeedback therapy combined with escitalopram for panic disorder ZHOU hao KONG Ling-jun LI long ( Ji-an Municipal Third Hospital Ji-an JIANGXI 343000 China) 【Abstract】Objective ：To investigate the clinical effect of biofeedback combined with escitalopram in the treatment of panic disorder. Methods ：80 cases patients were randomly divided into two groups，each group had 40 cases，the control group was given escitalopram treatment，the observation group in some basis with biofeedback treatment，the clinical results of two groups were retrospectively analyzed. Results ：The total effective rate of the observation group was87.5%，the total efficiency of the control group was 70.0%，the differences of the total efficiency between two groups were statistically significant(Plt;0.05).The HAMA scores before and after treatment of 1W had no significant difference (Pgt;0.05). The 2W had significant difference(Plt;0.05).4W，8W，the difference was significant (Plt;0.01).Evaluation of WHOQOL-100 before treatment had no significant difference(Pgt;0.05)，the two group after treatment were better than before treatment，during treatment of article 8W，the observation group social relationships， independence，psychological and physiological score was significantly higher than the control group，the difference was statistically significant(Pl