苏州市双相障碍患者精神药物使用现况调查.docVIP

精品论文 参考文献 苏州市双相障碍患者精神药物使用现况调查 （1.苏州市广济医院 江苏 苏州 215008；2.常熟市精神卫生中心 江苏 常熟 215500；3.太仓市精神卫生中心 江苏 太仓 215400） 【摘 要】目的：调查苏州市双相障碍患者精神药物治疗的现状。方法：采用横断面调查方法，使用患者药物使用调查表，对苏州市3家精神疾病专科医院的141例住院和门诊双相障碍患者进行调查，收集一般资料、临床特征及精神药物使用情况等数据。结果：⑴111例（78.7%）患者接受心境稳定剂治疗，使用居前三位的依次是丙戊酸钠（45.8%）、碳酸锂（33.3%）、拉莫三嗪（15.83%）；门诊患者丙戊酸钠、拉莫三嗪的使用剂量明显低于住院患者，差异具有统计学意义（P＜0.05）。⑵联合用药：有9例(6.4%)联合了第二种心境稳定剂；131例（92.9%）联合了抗精神病药，其中SGAs127例；另有41例（29.1%）联用了抗抑郁药物。⑶合并用药：双相障碍最常合并使用的药物是苯二氮卓类药物（25.6%）、抗胆碱能药(7.8%)、降血压药(7.8%)、降血糖药(3.5%)、升高血白细胞药物(2.8%)、通便药(2.1%)、降血脂药(2.1%)、beta;-受体阻断剂(1.4%)、保肝药(1.4%)。结论：心境稳定剂是双相障碍药物治疗的基础，联合第二代抗精神病药物是我市双相障碍药物治疗的主要方式。 【关键词】双相障碍，抗精神病药物；抗抑郁药物；心境稳定剂；抗焦虑药物；现况调查 【中图分类号】R74 【文献标识码】A 【文章编号】1004-6194（2015）02-0163-03 A cross-section survey on Psychotropic medication pattern of bipolar disorder patients in Suzhou Jianhong Shen, Yong Yang, Ruoshui Ding, ZhongYang, Xinda Wang, Xiangdong Du, Qiyi Mei 【Abstract】Objective: To investigate the present status of medication treatment for bipolar disorder patients in Suzhou. Method: 141 of inpatients and outpatients from three mental disease hospitals were involved in this investigation, using cross-section survey method and drug questionnaire in an effort to collect the data of general information, clinical features and the usage of psychotropics. Result:(1): 111(78.7%) cases were treated by mood stabilizers , the top three were valproic acid sodium (45.8%), lithium carbonate (33.3%) and lamotrigine (15.83%) respectively; the dosage of valproic acid sodium for outpatients was significantly and statistically lower than inpatients(Plt;0.05). (2): Drug combination: 9 cases (6.4%) combined with a second kind of mood stabilizer; 131 cases (92.9%) combined with antipsychotics including 127 cases with SGAs; 41 cases (29.1%) combined with antidepressants. (3) Medical augmentation : Bipolar disorder often augmented with benzodiazepines drugs (25.6%), anticholinergic drugs (7.8%), blood pressure medications (7.8%), antidiabetic agents (3.5%),