药物治疗联合关节镜下滑膜切除术对关节功能改善的影响.docVIP

精品论文 参考文献 药物治疗联合关节镜下滑膜切除术对关节功能改善的影响 （天津宁河县医院骨一科 天津 301500） 　　【摘要】 目的：探讨药物治疗联合关节镜下滑膜切除术对关节功能改善的影响。方法：将150例具有膝关节损伤的RA患者随机分为观察组(80例)、对照组(70例)。将观察组患者分为A期、B期、C期。对照组给予口服药物治疗；观察组给予关节镜下滑膜切除术和口服药物。比较两组患者手术后180天和360天进行健康评定(HAQ)、关节炎影响测量(AIMS)、关节功能评定(Ishikawa)、软骨损伤评定（Recht）。结果：观察组治疗后180天、360天HAQ、AIMS、Recht评分均低于对照组（P＜0.05）。结论：药物治疗联合关节镜下滑膜切除术对具有膝关节损伤的RA患者的关节具有改善作用，且越早进行关节镜下滑膜切除术其预后越好。 　　【关键词】 类风湿关节炎；关节功能；关节镜 　　【中图分类号】R684 【文献标识码】A 【文章编号】2095-1752（2016）29-0026-02 　　The impact of drug therapy combined with arthroscopic synovectomy on improve the joint function 　　LI Qiang. Department of One Orthopedics,Ninghe County Hospital,Tianjin 301500, China 　　【Abstract】Objective To explore the impact of drug therapy combined with arthroscopic synovectomy on improve the joint function. Methods One hundred and fiftypaints ofRA patients with knee injury were randomly divided into two groups: the observation group (n=80) andthe control group (n=70). The observationgroup were divided into threeperiod：A period、B period、C period. The control group were given oral medication.The control group were given arthroscopic synovectomy and the oral drug.Health assessment (HAQ), arthritis impact measurement (AIMS), joint function assessment (Ishikawa), cartilage damage assessment (Recht) were compared after 180 days and 360 days in surgery.ResultsAfter treatment of 180 days and 360 days,HAQ, AIMS, Recht Rating of the observation group were lower than that the control group（P＜0.05）. Conclusion Drug therapy combined with synovectomy Arthroscopic knee injury having RA patients with improved joint action. The sooner the arthroscopic synovectomy, the better the prognosis. 　　【Key words】Rheumatoid arthritis; The knee joint; Arthroscopic 　　关节炎是目前较为普遍的一类关节炎症性疾病，其中以类风湿性关节炎（RA）较为多见。RA在疾病的进展过程中常常可导致膝关节的损伤，如关节畸形或结构改变等，严重者甚至可导致活动不利，大大降低患者生活质量。目前关于RA的治疗，早期常采用口服药物疗法，后期采用关节滑膜切除，但通过查阅大量临床报道，目前关于药物联合关节镜下滑膜切除术治疗RA的报道较少。因此本研究比较药物治疗与药物联合关节镜下滑膜切除术对RA患者近远期疗效，旨在为日后临床提供依据。 　　1.资料与方法 　　1.1 一般资料