血象指标预测急性失代偿性心脏衰竭（ADHF）患者的一年死亡率.docVIP

精品论文 参考文献 血象指标预测急性失代偿性心脏衰竭（ADHF）患者的一年死亡率 王翠兰1 秦建斌2 孙晓东1 张丽莉1 郑宏1 1．抚顺市中心医院心血管内科 抚顺 113006；2．抚顺石化总医院内科 抚顺 113006 【摘 要】目的：本研究根据不同的血象指数预测急性失代偿性心脏衰竭（ADHF）患者的一年死亡率。方法：2013年9月和2015年1月在我院住院的ADHF患者，其收缩期左室射血分数le;40％，有临床症状和体征。进行回顾性研究。研究对象以1年死亡率为条件分为两组。结果：131例ADHF（平均年龄68plusmn;13岁，56％为男性）参加了这项研究。一年死亡发生率为30％。一年死亡的患者中血红蛋白水平，血小板，淋巴细胞和嗜碱粒细胞计数均显著降低，而红细胞分布宽度显著升高。嗜中性粒细胞，单核细胞，嗜酸性粒细胞计数在两个组中无明显差异。此外，肾小球滤过率（eGFR）是否降低及是否使用血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂（ACEI / ARB）与死亡率相关。结论：在血液学指标：血红蛋白水平，血小板和淋巴细胞计数对心衰患者一年的全因死亡率有预测意义 关键词 心力衰竭；血常规；死亡率 The importance of hematologic indices in the risk stratification of patients with acute decompensated systolicheart failure. Abstract Objective：This study aimed to investigate which of these parameters are useful in predicting one-year all-cause mortality in patients with acute decompensated?heart failure（ADHF）.Methods：A Patients who were hospitalized between January 2013-1月2015in our hospital with systolic-ADHF with ejection fraction le;40%，symptoms，and findings of congestion were enrolled retrospectively in the study.The study population was divided into two groups based on one-year-mortality.Results：131 patients with ADHF（mean-age 68plusmn;13 years；55% male）were enrolled in the study.One-year-mortality occurred in 30% of patients.Hemoglobin levels，platelet，basophil and lymphocyte counts were significantly lower，while red-cell distribution width（RDW）was found to be significantly higher in the one-year-mortality group.Neutrophil，monocyte，and eosinophil counts were similar in the two groups.Furthermore，lower estimated glomerular-filtration-rate（eGFR）and unused angiotensin-converting enzyme inhibitors/angiotensin receptor blockers（ACEI/ARB）were associated with mortalit.Conclusions：Among hematological indices；hemoglobin level，platelet and lymphocyte counts are readily available，useful and inexpensive markers for the prediction of one-year all-cause mortality in ADHF patients. Key words：mortality，acute decompensated?heart failure， 【中图分类号】R541.6+1【文献标识码】A【文章编号】2