贵州省2011-2015年流行性乙型脑炎实验室监测数据分析.docVIP

精品论文 参考文献 贵州省2011-2015年流行性乙型脑炎实验室监测数据分析 赵苏晔 叶绪芳 张丽 刘淳婷 　　贵州省疾病预防控制中心 550004 　　摘要：目的 分析贵州省2011-2015年流行性乙型脑炎（乙脑）网络实验室监测情况，为乙脑防控提供科学依据。方法 采用ELISA捕获法对贵州省2011-2015年报告乙脑疑似病例血液和脑脊液标本进行乙脑IgM抗体检测，对检测结果进行分析。结果 2011-2015年全省共报告乙脑疑似病例1536例；采集疑似病例标本1490例2380份，标本采集率为97.0%；检测疑似病例标本1490例2380份，乙脑IgM抗体阳性554例，阳性率为37.2%，2011-2015年乙脑IgM抗体的阳性率依次为48.0% ，41.4%，33.4%，25.9%，25.6%。省级乙脑实验室接受国家乙脑实验室及WHO的职能考核，成绩均为100分；省级乙脑实验室对全省网络实验室开展盲样考核和标本复核工作，符合率均在90%以上。结论 贵州省乙脑网络实验室质量控制良好，检测结果及时可靠，为流行性乙型脑炎的监测与控制提供有效的实验室数据。 　　关键词：流行性乙型脑炎；监测；分析 　　英文摘要 　　Abstract: Objective To analyze the Guizhou Province 2011-2015 Japanese encephalitis (JE) network monitoring laboratory conditions, and to provide the scientific evidence for the prevention and control of JE. Methods ELISA capture method of Guizhou Province 2011-2015 JE reported suspecting cases of blood and cerebrospinal fluid specimens for JE IgM antibody detection and analysis of test results. Results (2011-2015) across the province reported a total of JE 1536 suspected cases; acquisition suspected specimens were 1490 238 copies, specimen collection rate was 97.0%, detect suspected specimens were 1490 238 copies, JE IgM antibody positive 554 cases and positive rate of 37.2%, 2011-2015 JE IgM antibody positive rate in turn was 48.0%, 41.4%, 33.4%, 25.9% and 25.6%. Provincial JE laboratory received national JE laboratory and who function assessment, scores are 100 points; provincial JE Laboratory of the provinces network laboratory to conduct blind sample test specimens and review work, the coincidence rate in more than 90%. Conclusion Guizhou Province JE network laboratory quality control and test results in a timely manner to reliable, for monitoring and control of epidemic encephalitis B provides effective laboratory data. 　　Key words: Japanese encephalitis; surveillance; analysis 　　流行性乙型脑炎（乙脑）是一种由蚊虫叮咬引起的自然疫源性疾病，患者以高热、惊厥、昏迷、抽搐等为主要症状，病死率高严重者致残〔１〕。乙脑病例单靠临床诊断容易引起误诊〔2〕，实验室确诊尤其重要。贵州省是全国乙脑高发省份之一，自2006年建立了乙脑网络实验室。为了解贵州省乙脑网络实验室监测情况，对2011-2015年全省疑似乙脑病例标本监测情况进行分