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ageLOC SCienCe:
The geneTiCS
Of YOuTh
©2011 nu Skin
Tab Le Of COnTenTS
IntroductIon: the GenetIcs of Youth
sectIon 1: scIentIfIc research conducted bY nu sk In and/or
Its partners
Transcriptional Biomarkers of Age and Their Modulation by
Dietary Interventions
Antioxidation and Lifespan Extension Activities of Cordyceps Sinensis
Cs-4 in Oxidative Stress and Aging Models
Transcriptional Biomarkers of Mitochondrial Aging and Modulation
by Cordyceps Sinensis Cs-4
A Nutritional Strategy to Oppose the Genetic Expression of Aging
and Loss of Vitality
Targeting Age-Related Gene Expression Improves Mental and
Physical Vitality
Role of Mitochondria in Age-Related Hearing Loss and Its Prevention
by Caloric Restriction
sectIon 2: backGround research conducted bY Independent
partIes
IntroductIon: the GenetIcs of Youth
nu Skin brings together a world-class team of scientists who have conducted pioneering research in
their respective fields of anti-aging research for over 30 years. Collectively, they have published over
300 scientific papers, and their insights have changed the understanding of aging. Their work details the
genetic basis of aging while demonstrating that biological aging is no longer considered an inexorable
or inevitable process.
Together with these scientists we have developed ageLOC science, which targets the ultimate sources
of aging. With ageLOC science we better understand functional groups of genes related to aging (what
we call Youth gene Clusters or YgCs) and how to reset them to reflect a more youthful gene expres-
sion pattern.
The loss of vitality is one of the first
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