脉络丛neuro2a细胞株对胚胎脊髓运动神经元轴突的排斥作用-江苏大学.pdfVIP

18 3 ( ) Vo.l 18 No. 3 2008 5 Journal of Jiangsu University(M edicine Edition) M ay 2008 Neuro2 1 1 2 2 3 盛 鹏, 杨惠林 , 张志坚 , 龚爱华 , 刘锦波 ( 1. , 215006; 2. , 212013; 3. , 213003) [ ] : Neuro2 : ECM Gel , Neuro2 12, Neuro2 : N euro2 12 2, Neuro2 : Neuro2 [] Slit2; ; ; [] R338. 2 [ ] [] 1671- 7783( 2008)03- 0197- 04 Repelling effect of the choroid plexus, Neuro2A cells on embryonic spinalmotor axons 1 1 2 2 3 SH EN G P eng , YANG H uilin , ZHAN G Zh ij ian , GON G A ihua , L I U J inbo ( 1. Department ofOrthopaedics, theFirst ffiliatedHospital of Soochow University, Suzhou Jiangsu 215006; 2. School ofM edicine, JiangsuUni versity, Zhenjiang Jiangsu 212013; 3. Department of Orthopaedics, the ffiliated Second Hospital of Changzhou of NJMU, Nanjing Jiangsu 213003, China) [Abstract] Objective: To investigate the effect of the choroid plexus or the Neuro2 cells on the em bryonic spinalmotor axons.Methods: To useECM Gelas a tissue culture substrate, 3dmi ention coculture of the choroids plexus or the Neuro2 cellsw ith the ventral part of the embryonic spinalmotor column (Embryonic 12 days, E12)weremade in the substrate. To observe the effect of the choroid plexus or the Neuro2 cells on the embryonic spinalmotor axons. Results: fter 2 days of coculture, we found more spinalmotor axons were grown from the distal part of the choroid plexus or the Neuro2 cells. onclu sion: The choroid plexus and theNeuro2 cells had the repelling effecton embryonic