抗生素PPT课件（英文精品） Antibiotics(51p)PPT.pptVIP

Chapter 8 Antibiotics;Antibiotics as disturber with the biosynthesis of protein ;Tetracycline Antibiotics ;Tetracyclines are produced by actinomyces (放线菌), which have broad-antibacterial spectrum. The basic skeleton of tetracyclines is naphthacene ring. Tetracyclines differing from each other chemically only by substituent variation at positions 5,6 and 7.;Tetracycline pharmacophore and numbering ;;Tetracycline;Stability under acid condition;Formation of 4-Epitetracycline;Stability under base condition;Formation of metal chelates;Aminoglycoside Antibiotics ;The aminoglycoside class of antib