Phase Imaging on a .2 T MR Scanner Application to Temperature Monitoring During Ablation Procedures英文文献.pdfVIP

Original Research Phase Imaging on a .2-TMR Scanner: Application to Temperature Monitoring During Ablation Procedures Shantanu Sinha, PhD Thomas Oshiro, BS Usha Sinha, PhD Robert Lufkin, MD Proton phase shift imaging methods with keyholing Abbreviations: FA = flip angle, FLASH = fast low angle shot, FOV ifield were developed to rapidly monitor temperature during of view. FWHM = full width at half maximum, W = keyhole factor. PRF = MR-guided radiofrequency (RF) interventional proce- pmton resonance frequency. ROI = region of interesl, RF = rddiofmquency, dures on a .2-T open configuration scanner. Tempera- SNR = signal-to-noise ratio, TSNR = signal-to-noise ratio of the temperature ture calibration was performed on thermally controlled map. gel phantom and ex vivo bovine liver samples. Keyhol- ing methods were implemented for rapid imaging and THE INTRODUCTION OF the open magnet configuration tested both in simulation experiments and in the gel with wide angle accessibility to the patient and real time phantom. Phase drifts from extraneous sources were monitored and compensated for using reference phan- monitoring of images within the scanner room has toms. Sequence parameters TE, TR, and flip angle (FA) sparked considerable interest in MR-guided interventional were optimized for maximum temperature sensitivity procedures. Such procedures, including MR-guided biop- and minimum noise. Reduction of phase noise from sies, hyperthermia, cryoablation, and ablation using laser, coupling of the magnetic field to external perturba- radiofre