Analysis and Correction of Motion Artifacts in Diffusion Weighted Imaging英文文献.pdfVIP

Analysis and Correction of Motion Artifacts in Diffusion Weighted Imaging Adam W. Anderson, John C. Gore For diffusion-weighted magnetic resonance imaging and un- cialized hardware that is not widely available, and pre- der circumstances where patient movement can be modeled sents image quality problems of its own. In standard se- as rigid body motion, it is shown both theoretically and ex- quences, diffusion pulses can be designed to compensate perimentally that translations and rotations produce phase for velocity and higher order motion, although this dra- errors which are zero- and first-order, respectively, in position. matically reduces the sensitivity of the sequence to inco- Whlile a navigator echo can be used to correct the imaging herent motion as well. The field gradient strengths avail- data for arbitrary translations, only when the diffusion gradi- ent is applied inthe phase encode direction isthere sufficient able on whole body imaging systems are not large enough informationto correct for rotations around all axes, and there- to make gradient moment nulling an attractive solution. fore for general rigid body motion. Experimentsintest objects An elegant approach to the problem of patient transla- and human brain imaging confirm theoretical predictions and tion which combines pulse sequence design and postpro- demonstrate that appropriate corrections dramatically im- cessing has been proposed by Ordidge et al. (4,s). In this pralve image quality in vivo. method, a two echo-pulsed gradient spin-echo (PGSE) Key words: artifacts; diffusion-weighted imaging. experiment is performed. The first echo, which we will