Miniature Permanent Magnet for Table top NMR英文文献.pdfVIP

Miniature Permanent Magnet for Table-top NMR GIORGIO MORESI,1 RICHARD MAGIN2 1 Department of Physics and Astronomy, Institute of Physics, Condensed Matter Division, University of Basel, Klingelbergstrasse 82, CH-4056, Basel, Switzerland 2 Department of Bioengineering, University of Illinois at Chicago, Science and Engineering Office Building (M/C 063), 851 South Morgan, Chicago, Illinois 60607-7052 ABSTRACT: The multi-infinity dipole magnet is a new design capable of generating a relatively high and homogeneous permanent magnetic field (0.1–3 Tesla and homogeneity 20 ppm for 3 mm) that is suitable for nuclear magnetic resonance (NMR) or electron spin resonance (ESR) studies of small volume chemical or biological samples. The theoretical design and practical aspects involved in the construction of a prototype tabletop NMR system (0.6 T and homogeneity of 10 ppm in a ellipsoidal region of 3 3 5 mm3) are described. A simple NMR relaxation time experiment was performed on a water sample doped with 40 mM of CuSO4. This system in its current configuration is suitable for relaxation time studies of materials or for educational use. The introduction of shim coils would increase the homogeneity of the magnet by a factor of 100, allowing the system to be used as a portable NMR spectrometer. In addition the introduction of gradient coils between the poles would transform the spectrometer to a MRI portable system for tissue analysis or simple MR microimaging at fields up to 3 T. © 2003 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 19B: 35–43, 2003 KEY WORDS: micro-imaging; microcoils; perman