药物合成反应作业幻灯片.pptxVIP

Total Synthesis of Amphirionin 4;CONTENT;Amphidinium species of marine dinoflagellates;;Amphidinium-4;Retrosynthetic Analysis for Amphirionin-4 (1);The structure of three key intermediates三个关键的中间体的结构;Synthesis route of compound 12-13化合物12-13的合成路线;Synthesis route of compound 13-14化合物13-14的合成路线;化合物14-15的合成路线;中间体34的合成;化合物22-23的合成路线;化合物23-25的合成路线;化合物26的合成;Scheme 4. Synthesis of the Vinyl Halides 23 and 26;Table 1. Cross-coupling Reactions to Access Diene 30;中间体33的合成路线;Unfortunately, all attempts to remove the TBS protecting group from this material resulted in decomposition.;化合物34-38的合成路线;化合物